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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Effect of Strain Fields on Frequency Band Gaps of Periodic Lattice-Based Metamaterials
منشور في 2024"…Lattice-based metamaterials, known for their ability to deliver unique acoustic properties such as wave band gaps and direction-dependent phase velocities, are considered promising for noise filtering and acoustic sensor applications. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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On the Optimization of Band Gaps in Periodic Waveguides
منشور في 2025"…Across both cases, the effect-size analysis (Cliff’s) confirms that observed gaps are generally small to medium at moderate budgets and tend to narrow at higher budgets as solutions converge. …"
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CO, CO2, and SO2 detection based on functionalized graphene nanoribbons: First principles study
منشور في 2020"…In this study, density functional theory (DFT) has been used to build armchair graphene nanoribbon (AGNR) gas sensor and study its capacity to detect carbon monoxide (CO), carbon dioxide (CO2), and sulfur dioxide (SO2) gases. …"
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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
منشور في 2025"…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…"
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CO, CO<sub>2</sub>, and SO<sub>2</sub> detection based on functionalized graphene nanoribbons: First principles study
منشور في 2020"…<p dir="ltr">In this study, density functional theory (DFT) has been used to build armchair graphene nanoribbon (AGNR) gas sensor and study its capacity to detect carbon monoxide (CO), carbon dioxide (CO<sub>2</sub>), and sulfur dioxide (SO<sub>2</sub>) gases. …"
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Bridging the Gap between Theory and Practice of Inclusion in the United Arab Emirates
منشور في 2007"…The country itself is a fairly new developing country which was declared around thirty six years ago. The UAE has made significant progress in different areas including education. …"
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Harnessing microalgae for a synergistic approach to CO₂ capture, wastewater treatment, and biodiesel production: A review
منشور في 2025"…Innovative cultivation strategies including high-rate algal ponds, membrane <u>bioreactors</u>, and CO₂-enriched <u>flue gas</u> significantly enhance productivity and resource efficiency. …"
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Statistical analysis of air-gap membrane desalination experimental data: Hypothesis testing
منشور في 2015"…In this work, a complete set of experimental data on air gap membrane distillation is analyzed using statistical methods. …"
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COVID-19 (SARS-CoV-2) outbreak monitoring using wastewater-based epidemiology in Qatar
منشور في 2021"…The trend in Ct values in the wastewater samples mirrored the number of new daily positive cases officially reported for the country, confirmed by RT-qPCR testing of naso-pharyngeal swabs. SARS-CoV-2 RNA was detected in 100% of the influent wastewater samples (7889 ± 1421 copy/L – 542,056 ± 25,775 copy/L, based on the N1 assay). …"