Renal Function Decline in Recipients and Donors of Kidney Grafts حسب Bahous, Sola Aoun

"…Later decline was significantly associated with donor age and aortic stiffness. …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…Addition of N-acetyl-cysteine (NAC); being a reactive oxygen species (ROS) scavenger, led to a significant decrease in the cytotoxicity of arginine deprivation to U251 and A172 cells, indicating that ROS generation reversed the cytotoxicity of arginine deprivation to GBM cells. …"
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

"…<p dir="ltr">Acute lymphoblastic leukemia (ALL) is a significant cancer of children resulting from the clonal proliferation of lymphoid precursors with arrested maturation. …"

Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>) حسب Roberta Giordo (299595)

"…Mechanistically, we further showed that resveratrol inhibits ROS increase, prevents mitochondrial membrane potential dysfunction, and counteracts cell apoptosis/necrosis elicited by ZnO NP. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…In addition, we established the antitumor effects of SNG through reactive oxygen species (ROS) production, as inhibiting ROS production prevented the apoptosis-inducing potential of SNG. …"

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. …"

Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back حسب Lenka Koklesova (18102994)

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …"
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

"…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation حسب Feng, Samuel

"…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …"
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Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model حسب Kobeissy, Firas

"…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …"
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The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells حسب Fayad, Christelle

"…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma Younes (6424865)

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"

Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients حسب Alessandro Giuseppe Fois (2901365)

"…IPF sera-induced cellular effects were significantly blunted in cells exposed to the NADPH oxidase inhibitor diphenyleneiodonium (DPI) proving the causative role of ROS and suggesting their potential cellular source. …"

Battery Energy Management Techniques for Electric Vehicle Traction System حسب AbdelAziz, Ahmed Sayed AbdelAal

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Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma حسب Azar Atallah, Shirine

"…Reactive oxygen species (ROS) detection assay did not show a significant involvement of oxidative stress in the cytotoxicity of COE. …"
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Drug-free phototherapy of superficial tumors حسب Mehanna, Stephanie

"…When tested on a DMBA/TPA skin carcinogenesis model, a 90-min exposure to white light thrice weekly resulted in a significant decrease in tumor volumes/incidence compared to control and cisplatin groups, and restored normal morphological features, as confirmed by histopathology. …"
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Sternbergia Clusiana Bulb Ethanolic Extracts Induce Apoptosis in MCF-7 Breast Cancer Cells حسب Elias, Nazira

"…Moreover, SbBEE exposure caused a significant reduction in ROS production proposing a potent anti-oxidant potential. …"
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