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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
منشور في 2025"…This paper introduces a novel random vector functional link transformer (RFT) and ensemble deep random vector functional link transformer (edRFT) networks to capture the dynamic characteristics of significant wave heights. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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An Efficient Test Vector Compression Technique Based on Geometric Shapes
منشور في 2001"…The proposed scheme is based on ordering the test vectors in such a way that enables the generation of geometric shapes that can be highly compressed via perfect lossless compression. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Differential Flatness-Based Performance Enhancement of a Vector Controlled VSC With an LCL-Filter for Weak Grids
منشور في 2021"…<p>In this paper, a novel single-loop flatness-based controller (FBC) is proposed to control the grid-side current in a shunt converter connected to a weak grid through an LCL-filter. …"
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On Test Vector Reordering for Combinational Circuits
منشور في 2004"…In this paper, we propose an efficient test vector reordering technique that significantly reduces both the time and memory complexities of reordering procedures based on fault simulation without dropping. …"
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On test vector reordering for combinational circuits
منشور في 2004"…In this paper, we propose an efficient test vector reordering technique that significantly reduces both the time and memory complexities of reordering procedures based on fault simulation without dropping. …"
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Anomaly Detection Based Framework for Profile Monitoring
منشور في 2023احصل على النص الكامل
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Assessing Factors Influencing Customers’ Adoption of AI-Based Voice Assistants
منشور في 2024"…<p dir="ltr">The study aims to assess the factors that engage and accentuate usage pertaining to consumers with artificial intelligence-based voice assistants. …"
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Environment, Education, and Personality Innovation Based Index
منشور في 2022احصل على النص الكامل
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Critical Success Factors of Technology-based Start-ups in the UAE: The Moderating Role of the Organizational Life Cycle
منشور في 2025"…This study examines the Critical Success Factors (CSFs) influencing the performance and sustainability of Technology-based Start-ups (TBS) in the United Arab Emirates (UAE), while examining the moderating effect of the Organizational Life Cycle (OLC). …"
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Ensemble Deep Random Vector Functional Link Neural Network for Regression
منشور في 2022"…Subsequently, we propose a novel regularization method [boosted factor (BF)], two dRVFLs variants [edRVFL with skip connection (edRVFL-SC) and edRVFL with random skip connections (edRVFL-RSC)] and one strategy [ensemble skip connection edRVFL (esc-edRVFL)] which show significant improvement over the original dRVFL. …"