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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
منشور في 2009"…The inotropic response to maximal β-adrenergic stimulation was reduced by ≈54% in isolated hypertrophied hearts, along with a ≈32% decrease in subsarcolemmal cAMP levels in hypertrophied myocytes. …"
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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Cyclic nucleotide-gated (CNG) channels were used to monitor cAMP. The whole cell patch-clamp technique was used to record the associated CNG current (ICNG) and ICa,L. …"
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Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes
منشور في 2005"…Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …"
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Transport, magnetic and structural properties of(Tl0.5Pb0.5)Sr2-xCexCa2Cu3Oy compounds
منشور في 2000"…Resistivity, DC magnetization and X-ray diffraction measurements were performed on 6 sample with nominal composition (Tl0.5Pb 0.5)Sr2-xCexCa2Cu3 Oy, with x=0.0, 0.1, 0.2, 0.3, 0.4 and 0.5. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Differential water quality in confined and free-flowing water bodies, Lebanon
منشور في 2003"…Measured water parameters were temperature, pH, conductivity, BOD, HCO3-, Ca2+, Mg2+, Cl-, SO42-, PO43-, NO3-, NH3, Fe, Mn, Zn, Pb, and Cd. …"
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Effects of electrolytes and suwannee river humic acid on the aggregation behavior of silicon nanoparticles
منشور في 2017"…The aggregation rates in the presence of SRHA were higher than that in the absence of SRHA at the same Ca2+ concentrations and the critical coagulation concentrations (CCC) decreased from 0.4 M to 0.1 M. …"
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Chemical and microbiological investigations of metal ion interaction with norfloxacin
منشور في 1992"…This report describes a spectrophotometric study on the interaction between norfloxacin (NFX) and metal ions (Al3+, Mg2+ and Ca2+). Two buffers of pH 3.6 and 8.8 were used. …"
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Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
منشور في 2003"…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …"
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Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes
منشور في 2010"…The destabilization was attributed to bridging of the nanoparticles by the alginate–Ca2+ system. Results from this study suggest that various NOM and electrolytes play significant and differing roles in the aggregation of boron nanoparticles in natural aquatic environments.…"
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Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
منشور في 2017"…In this study, we report the thermoelectric power (TEP) measurements of Cu0.5Tl0.5Ba2Ca2Cu3O10-δ added with BaSnO3 nanoparticles. BaSnO3 nanoparticles were prepared by chemical co-precipitation method, while (BaSnO3)x/(CuT1)-1223 superconducting samples with 0.00 ≤ x ≤ 1.50 wt% were prepared using the solid-state reaction method. …"
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Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation
منشور في 2019"…TL and SKF inhibited chemotactic peptide fMLP-induced response linked to TRPV2 Ca2+ activity, and down-regulated expression of surface marker CD38 involved in leukemia and lung airway inflammation. …"
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
منشور في 2014"…The diameter and length of the Pipeline Embolization Device were measured at both time points and compared for determination of the device changes. …"
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