يعرض 1 - 20 نتائج من 351 نتيجة بحث عن '(( 1 _ decrease ) OR ( _ can decrease ))~', وقت الاستعلام: 0.11s تنقيح النتائج
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7

    Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives حسب Zeiz, Ali

    منشور في 2023
    "…Introduction: The anticancer and anti-inflammatory activities of a novel series of eleven pyrimido[1,2-b]pyridazin-2-one analogues substituted at position 7 were assessed in the current study. …"
    احصل على النص الكامل
    احصل على النص الكامل
  8. 8

    Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. حسب Padmanabhan, Regina

    منشور في 2022
    "…In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. Our data show that a combination therapy of TZ and BMS-202 can significantly reduce the viability of ZR75 cells and trigger several morphological changes. …"
    احصل على النص الكامل
    احصل على النص الكامل
  9. 9

    Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes حسب Jung, Sungwook

    منشور في 2023
    "…Immune therapeutics holds great promise in the treatment of type 1 diabetes (T1D). Nonetheless, their progress is hampered by limited efficacy, equipoise, or issues of safety. …"
    احصل على النص الكامل
    احصل على النص الكامل
  10. 10
  11. 11

    Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

    منشور في 2015
    "…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …"
    احصل على النص الكامل
  12. 12

    Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

    منشور في 2022
    "…However, this process remains inefficient since only a small percentage of transfected cells can undergo full reprogramming. Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. …"
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
  13. 13

    Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. حسب Al-Jaber, Hend

    منشور في 2024
    "…Other insulin resistance-related phospho-proteins (GSK3B, mTOR, PTEN) increased with IL-6, 4HNE, TNFα, and high insulin under hypoxia, while p-IRS1 levels remained unaffected. In summary, different in vitro models using inflammatory, oxidative stress, and high insulin conditions under hypoxic conditions can capture various aspects of in vivo adipose tissue insulin resistance (IR). …"
    احصل على النص الكامل
    احصل على النص الكامل
  14. 14
  15. 15

    Gender Prespecified Sampling for Cost Control حسب Trung Le1, Kien

    منشور في 2014
    "…An alternative fieldwork technique commonplace in the region is to have teams of interviewers in the field. The team can include one of each gender, one male and two female interviewers, or one male and three female interviewers. …"
    احصل على النص الكامل
    احصل على النص الكامل
  16. 16

    Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes حسب Younes, Noura B.

    منشور في 2022
    "…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. Moreover, DHA-treatment of hypoxic cells caused a decreased secretion of pro-inflammatory markers (IL-6, MCP-1) and leptin and increased adiponectin secretion compared with hypoxic cells. …"
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
  17. 17

    Vitamin K1 as a potential molecule for reducing single-walled carbon nanotubes-stimulated �-synuclein structural changes and cytotoxicity حسب Naskhi A.

    منشور في 2019
    "…Conclusion: It may be concluded that vitamin K1 decreases the propensity of �-syn aggregation in the presence of SWCNTs and induction of cytotoxicity.…"
    احصل على النص الكامل
    احصل على النص الكامل
  18. 18
  19. 19

    Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

    منشور في 2018
    "…Results of CGRP are in line with TRPV-1, as a downstream regulatory effect. NOS system and transient receptor potential (TRP) channels can contribute to DPP-4 inhibition-mediated cardioprotection against I/R injury using Sitagliptin.…"
    احصل على النص الكامل
    احصل على النص الكامل
  20. 20

    Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation. حسب Saleh, Alaaeldin I

    منشور في 2018
    "…Our findings indicate that EA plant extract can reduce human oral cancer progression by the inhibition of angiogenesis and cell invasion via Erk1/Erk2 signaling pathways.…"
    احصل على النص الكامل
    احصل على النص الكامل