Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…We measured the levels of neutralizing total antibodies (NtAbs), anti-S-RBD IgG, and anti-S1 IgA titers among VN and NI up to ∼10 months from administration of the first dose, and up to ∼7 months from SARS-CoV-2 infection, respectively. …"
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

"…FindingsWe pooled 1479 studies that had measured the blood pressures of 19·1 million adults. …"
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. حسب Sara, Sokary

"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …"
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…"
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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…Approximately one-third of the HAP-attributable burden (518·1, 410·1–641·7) was mediated via short gestation and low birthweight. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system حسب Mohammadreza, Gholami

"…Microgrids (MGs) are gaining popularity due to their ability to provide reliable and resilient power supply, especially when integrated with renewable energy sources (RESs) and battery energy storage systems (BESS). Reliability is a critical factor for MG owners and policy makers. …"
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

"…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …"
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Electric vehicles charging management using deep reinforcement learning considering vehicle-to-grid operation and battery degradation حسب Mostafa M., Shibl

"…The EV chargers are considered the RL environment and the EV users are considered the RL agent. Finally, the system was tested with a range of case studies using real-life EVs charging data, which proved the effectiveness and reliability of the system to protect the distribution grid and satisfy the EV user’s charging requirements.…"
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Production of flexible nanocomposite membranes for x-ray detectors حسب Ahmad I., Ayesh

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Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture حسب Slimani, Ahmed

"…Isothermal relaxation from the optically induced high spin state of the core back to the low spin state and activation energies associated with the transition between these states were measured. The presence of a shell decreases the activation energy, which is associated with the elastic properties of the core. …"
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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan حسب Hiroaki, Nishiuchi

"…Lane markings are considered an essential component of a road system. As highlighted in previous studies, they are directly linked to efficiency and safety. …"
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach حسب Hoda, Hosseini

"…However, biological contamination is one of the most critical problems associated with large scale algal production, especially in open systems such as raceway ponds. …"
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Energy saving potential analysis applying factory scale energy audit – A case study of food production حسب Derar, Al Momani

"…This has allowed a reduction in energy use of up to 18%. The CO2 harmful emissions were also decreased. …"
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials حسب Pieter Francsois, Fouche

"…This meta-analysis indicated an 11% decrease in the death risk at 1 month after TXA use (odds ratio [OR] 0.89, 95% confidence interval [CI] 0.84 to 0.95) with a number needed to treat of 61 to avoid 1 additional death. …"
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation حسب Feng, Samuel

"…Oxidative stress (OS) has been shown to have a negative effect on the autonomic nervous system (ANS) and on ANS modulation of heart rate. …"
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 حسب Sirota, Sarah Brooke

"…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …"
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... حسب Haidong, Wang

"…HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. …"
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