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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
منشور في 2017"…XTT cell viability assay, which detects the presence of metabolically active cells, was used to assess cell proliferation. A decrease in proliferation of KG-1 cells was observed upon treatment with both forms of vitamin E derivatives; however, β-T3 was more potent than γ-T3 in promoting cell death with lower IC50 values. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…Here we show that hippuristanol, a compound that impedes eIF4A in a manner distinct from PatA, similarly inhibits the iNOS/NO pathway and cytokine-induced muscle wasting. …"
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
منشور في 2020"…IntroductionAntiretroviral therapy (ART) is considered the most effective way to prevent perinatal transmission of human immunodeficiency virus (HIV). However, there is little knowledge about the effect of ART on the brain of HIV uninfected children born to HIV infected mothers (HUC). …"
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
منشور في 2024"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series
منشور في 2024"…In multivariable Poisson interrupted time series regression, the COVID-19 lockdown was associated with a 27% decrease in the monthly numbers of HIV tests (IRR 0.73, 95%CI 0.72–0.73), a 25% decrease in HIV positive tests (IRR 0.75, 95%CI 0.71–0.79), and a 43% reduction in ART initiations (IRR 0.57, 95%CI 0.55–0.60). …"
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …"
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Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution
منشور في 2011احصل على النص الكامل
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
منشور في 2022"…The present study was conducted using four different genotypes of B. oleracea named as FD-3, FD-4, FD-2 and Ceilo Blanco which were subjected to the Cd stress at various concentrations i.e., 0, 5, 10 and 20 µM with or without the application of NO i.e., 0.10 mM in the sand containing nutrient Hoagland’s solution. …"
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…Fish (n = 300, initial body weight = 10.02 g ± 0.11 g) received supplementary CURNPs at rates of 0 (control; CURNPs0), 50 (CURNPs50), 100 (CURNPs100) and 150 (CURNPs150) mg/kg diet for 90 days. …"
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Application of Fe<sub>3</sub>O<sub>4</sub> magnetite nanoparticles grafted in silica (SiO<sub>2</sub>) for oil recovery from oil in water emulsions
منشور في 2021"…An excellent %<sub>hdem</sub> 90% was achieved C<sub>oil</sub> in the range 50 e2000 mg/L. Using an MD<sub>dose</sub> as low as 10 mg/L attained a %<sub>hdem</sub> in the range of 93% - 4.3% for O/W mixtures with C<sub>oil</sub> < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …"
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Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
منشور في 2019"…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …"
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Notes total mesorectal excision (TME) for patients with rectal neoplasia
منشور في 2014"…Methods NOTESTME was attempted in 16 patients with distal rectal neoplasia (i.e., distal edge of the tumor lower than the pouch of Douglas, between 0 and 12 cm from the dentate line). …"
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