A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact حسب Samer Gowid (15955152)

"…<p dir="ltr">This paper aims to develop a robust and practical photovoltaic (PV) Maximum Power Point (MPP) identification tool developed using reliable experimental data sets. …"

Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country حسب Mohamad Y. Khatib (11659459)

"…Factors independently associated with mortality included older age ([OR]; 2.3 [95% CI; 1.92–2.75] for each 10-year increase in age, <i>p</i> < 0.001), chronic kidney disease (OR; 1.9 [95% CI; 1.02–3.54], <i>p</i> = 0.04), active malignancy (OR; 6.15 [95% CI; 1.79–21.12], <i>p</i> = 0.004), lower platelet count at ICU admission (OR; 1.41 [95% CI; 1.13–1.75] for each 100 × 103/µl decrease, <i>p</i> = 0.002), higher neutrophil-to-lymphocyte ratio at admission (OR; 1.01 [95% CI; 1–1.02] for each 1- point increase, <i>p</i> = 0.016), higher serum ferritin level at admission (OR; 1.05 [(95% CI; 1.02–1.08] for each 500 µg/L increase, <i>p</i> = 0.002), and higher serum bilirubin level at admission (OR; 1.19 [95% CI; 1.04–1.36] for each 10 μmol/L increase, <i>p</i> = 0.01). …"

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Amira Othman (380131)

"…<p dir="ltr">The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S. El-Shoukrofy (19646815)

"…The two most effective 15-LOX inhibitors, <b>2a</b> and <b>2b</b>, exhibited 69 % and 57% of quercetin's action, respectively. …"

Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm حسب Ali S. Alghamdi (17541711)

"…This has been done using a new meta-heuristic algorithm, improved artificial rabbits optimization (IARO). …"

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase حسب Ahmed S. Ibrahim (10049522)

"…Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …"

A dramatized method for teaching undergraduate students responsible research conduct حسب Kuei-Chiu Chen (14108854)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold حسب Youmna Elsayed Hassanein (21547490)

"…A 25% decrease in MFO in HYPO (0.25 ± 0.08g.min^-1) compared to NORM (0.35 ± 0.08g.min-1; <i>P</i> < 0.001; <i>d</i> =1.24) was observed. …"

Anabolic steroids-induced delirium حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Psychiatric aspects are of particular importance and include psychosis, delirium, mania, depression, and aggression. We describe the case of a young gentleman who was managed as a case of androgenic steroid induced delirium.…"

Acute spasticity in malignant MCA stroke: a case report and review of literature حسب Muhammad Faizan (12710607)

"…However, an acute onset of spasticity at presentation is extremely rare. We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. …"

Old subjects with sepsis in the emergency department: trend analysis of case fatality rate حسب Andrea Fabbri (356760)

"…<h3>Background</h3><p dir="ltr">The burden of sepsis represents a global health care problem. We aimed to assess the case fatality rate (CFR) and its predictors in subjects with sepsis admitted to a general Italian hospital from 2009 to 2016, stratified by risk score.…"

Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance حسب Mohammed Hamidat (3722086)

"…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …"

A Case Study to Identify the Hindrances to Widespread Adoption of Electric Vehicles in Qatar حسب Amith Khandakar (14151981)

A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries حسب Hania Sami (21436013)

"…The coexistence of the two is extremely rare and has a poorer prognosis. Our case report is one of the first to report burn injuries as a trigger factor for EF and generalized morphea overlap. …"

Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

"…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…"

Effectiveness of 2D magnesium phosphate hydrogel for surgical decontamination of dental implants: A case series حسب Sara Behmanesh (22391968)

"…The study encompassed eight cases with a history of peri‐implantitis. Clinical measurements were recorded before and after treatment, including bleeding on probing, suppuration, and probing depth. …"