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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …"
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Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (Co<sub>x</sub>Fe<sub>1−x</sub>Fe<sub>2</sub>O<sub>4</sub>) with theoretical...
منشور في 2023"…An environmental friendly method of co-precipitation is applied to generate Co<sub>x</sub>Fe<sub>1−x</sub>Fe<sub>2</sub>O<sub>4</sub> with variable dopant concentration (x = 0–0.8), which is deeply investigated by structural and functional property analyses of the ferrofluids. …"
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…Topotecan treatment caused a specific cell-cycle arrest at the S phase in addition to an increase in the percentage of cells in the preG phase. These alterations in cell cycle progression were further enhanced upon andrographolide pre-treatment: the percentage of cells in the S-phase reached 40.4%, compared to 19.3% upon treatment with topotecan alone. …"
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Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing <i>via</i> stereolithography
منشور في 2025"…Notably, pure PMMA exhibited the highest tensile strength, 26.23 ± 0.14 MPa and an elastic modulus of 707.81 MPa, while PMMA resin/1% Mg showed the lowest strength (19.46 ± 0.25 MPa) and modulus (392.88 MPa), indicating a decrease in mechanical integrity with higher Mg content. …"
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Dielectric Properties of Y3Fe5O12 (YIG) Prepared at Different Molarities of NaOH
منشور في 2020"…In this study, Yttrium Iron Garnet (Y3Fe5O12) (YIG) powders were synthesized via co-precipitation method, followed by calcining the precipitates at 1100˚C. …"
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients
منشور في 2021"…</p><h3>Results</h3><p dir="ltr">Two hundred-eighty CKD patients (HD = 223 and pre-dialysis = 57) were included in the analyses (response rate 60.9%). …"
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Removal of Benzene and Toluene from Synthetic Wastewater by Adsorption onto Magnetic Zeolitic Imidazole Framework Nanocomposites
منشور في 2022"…Thus, by performing the present study, the potential of Fe<sub>3</sub>O<sub>4</sub>/zeolite imidazolate framework nanoparticles (Fe<sub>3</sub>O<sub>4</sub>@ZIF-8) was evaluated for the adsorption of benzene and toluene. …"
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Evidence of a universal relation between electron-mode coupling and �� in Ba1−�K�Fe2As2 superconductor from laser angle-resolved photoemission spectroscopy
منشور في 2014"…We performed a laser angle-resolved photoemission spectroscopy (ARPES) study on a wide doping range of the Ba1−KFe2As2 (BaK) iron-based superconductor. We observed a robust low-binding energy (BE) kink structure (kink1) in the dispersion which is doping dependent whereby its energy peaks at the optimally doped level (∼0.4) and decreases towards the underdoped and overdoped sides. …"
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…Furthermore, confocal microscopy analysis of BODIPY-stained untreated, steatotic, and Ex-4-treated steatotic cells showed that Ex-4 significantly decreases the number of lipid droplets. Fatty acid uptake and transport genes were also affected by MALAT1 knockdown. …"