بدائل البحث:
5 point » _ point (توسيع البحث), a point (توسيع البحث), 3d point (توسيع البحث)
_ fold » _ food (توسيع البحث)
5 non » _ non (توسيع البحث), a non (توسيع البحث), b non (توسيع البحث)
5 point » _ point (توسيع البحث), a point (توسيع البحث), 3d point (توسيع البحث)
_ fold » _ food (توسيع البحث)
5 non » _ non (توسيع البحث), a non (توسيع البحث), b non (توسيع البحث)
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
منشور في 2019"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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The maxima in northerly wind speeds and wave heights over the Arabian Sea, the Arabian/Persian Gulf and the Red Sea derived from 40 years of ERA5 data
منشور في 2020"…We have analyzed climatology and trends of northerly maximum wind speed and significant wave height (Hs) in the Arabian Sea and the connected marginal seas, Arabian/Persian Gulf and the Red Sea, during non-monsoon season derived from 40 years of ERA5 wind and wave data, and estimated monthly, annual and decadal extreme climate and their trends. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
منشور في 2017"…In vivo transient depletion of PRMT5 decreased intracranial tumour size and growth rate in mice implanted with both primary tumour-derived GBMNS and GBMDC. …"
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Effect of octylphenol polyethylene oxide on the corrosion inhibition of steel in 0.5 M H2SO4
منشور في 2004"…A non-ionic surfactant, octylphenol polyethylene oxide (OPPEO), was evaluated as an inhibitor for corrosion of low-carbon steel in 0.5M H 2SO4. …"
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Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells
منشور في 2021"…The study of any intervention able to counteract SARS-CoV-2 pandemic is considerably envisaged. It was previously shown, in in vitro models of infections, that the LED blue light is able to decrease the viral load of HSV-1 and ZIKV. …"
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Sliding mode control based dtc of sensorless parallel-connected two five-phase pmsm drive system
منشور في 2018"…This paper presents a sensorless direct torque control (DTC) combined with sliding mode approach (SM) and space vector modulation (SVM) to achieve mainly a high performance and reduce torque and flux ripples of a parallel-connected two five-phase permanent magnet synchronous machine (PMSM) drive system. …"
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
منشور في 2021"…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …"
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Wind energy potential along the onshore and offshore Qatar
منشور في 2020"…The present study aims at investigating the wind energy potential at select coastal locations of Qatar using ERA5 winds. ERA5 is the updated reanalysis product of the European Centre for Medium-range Weather Forecasts (ECMWF), in which the scatterometer and in situ wind data are assimilated to improve the accuracy of predictions, thus the long-term and short-term variabilities are reasonably well captured. …"
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Structural evaluation, preliminary in vitro stability and electrochemical behavior of apatite coatings on Ti6Al4V substrates
منشور في 2016"…As a result of SBF treatment, the apatite layer was found to remodel through a dissolution-precipitation mechanism due to its amorphous and non-stoichiometric nature, forming a smooth layer with better homogeneity and decreased surface roughness. …"
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system
منشور في 2016"…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …"
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Pollution Characteristics of Particulate Matter (PM2.5 and PM10) and Constituent Carbonaceous Aerosols in a South Asian Future Megacity
منشور في 2020"…The future megacity of Faisalabad is of prime interest when considering environmental health because of its bulky population and abundant industrial and anthropogenic sources of coarse particles (PM10) and fine airborne particulate matter (PM2.5). The current study was aimed to investigate the concentration level of PM2.5 and PM10, also the characterization of carbonaceous aerosols including organic carbon (OC), elemental carbon (EC) and total carbon (TC) in PM2.5 and PM10 samples collected from five different sectors (residential, health, commercial, industrial, and vehicular zone). …"
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An Eco-Friendly Quaternary Ammonium Salt as a Corrosion Inhibitor for Carbon Steel in 5 M HCl Solution: Theoretical and Experimental Investigation
منشور في 2022"…The influence of Q-22 on the corrosion behavior of C-steel was elucidated using non-destructive electrochemical measurements. The overall results revealed that adding varied concentrations of Q-22 significantly decreases the corrosion rate of C-steel. …"
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