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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
منشور في 2019"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts
منشور في 2018"…The aim of this work is to find a potential way for great decrease in CO2 capture energy requirement. Here, for the first time, a series of bifunctional Al2O3/HZSM-5 catalysts (Al-ZSM) were prepared by the combined precipitation ultrasound method and used for the CO2 desorption process. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
منشور في 2017"…In vivo transient depletion of PRMT5 decreased intracranial tumour size and growth rate in mice implanted with both primary tumour-derived GBMNS and GBMDC. …"
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Effect of octylphenol polyethylene oxide on the corrosion inhibition of steel in 0.5 M H2SO4
منشور في 2004"…A non-ionic surfactant, octylphenol polyethylene oxide (OPPEO), was evaluated as an inhibitor for corrosion of low-carbon steel in 0.5M H 2SO4. …"
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Sliding mode control based dtc of sensorless parallel-connected two five-phase pmsm drive system
منشور في 2018"…This paper presents a sensorless direct torque control (DTC) combined with sliding mode approach (SM) and space vector modulation (SVM) to achieve mainly a high performance and reduce torque and flux ripples of a parallel-connected two five-phase permanent magnet synchronous machine (PMSM) drive system. …"
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Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution
منشور في 2020"…The present work studied the effect of temperature on the corrosion behavior of API X120 steel in a saline solution saturated with CO2 in absence and presence of polyethyleneimine (PEI) as an environmentally safe green inhibitor. …"
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
منشور في 2021"…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …"
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Reactive Absorption of CO2 Using Ethylaminoethanol Promoted Aqueous Potassium Carbonate Solvent
منشور في 2016"…The N2O analogy was employed for the determination of H_(CO2) in the APCE solvent. The H_(CO2) was observed to be decreased by 5 and 31% due to the increase in the EAE concentration from 0.6 to 2 kmol/m3 and reaction temperature from 303 to 318 K, respectively. …"
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Wind energy potential along the onshore and offshore Qatar
منشور في 2020"…The present study aims at investigating the wind energy potential at select coastal locations of Qatar using ERA5 winds. ERA5 is the updated reanalysis product of the European Centre for Medium-range Weather Forecasts (ECMWF), in which the scatterometer and in situ wind data are assimilated to improve the accuracy of predictions, thus the long-term and short-term variabilities are reasonably well captured. …"
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Absorption of CO2 in aqueous blend of methyldiethanolamine and arginine
منشور في 2020"…However, for CO2 partial pressure of above 20 kPa, the addition of Arg caused a decrease in the solubility of CO2. …"
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Structural evaluation, preliminary in vitro stability and electrochemical behavior of apatite coatings on Ti6Al4V substrates
منشور في 2016"…As a result of SBF treatment, the apatite layer was found to remodel through a dissolution-precipitation mechanism due to its amorphous and non-stoichiometric nature, forming a smooth layer with better homogeneity and decreased surface roughness. …"
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Screening of Qatari Microalgae and Cyanobacteria for Application in CO2 Utilization
منشور في 2018"…The tolerance of the strains to increased concentrations of CO2 in the gas phase was also studied for CO2 concentrations ranging from 5% to 30% (v/v). …"
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An Eco-Friendly Quaternary Ammonium Salt as a Corrosion Inhibitor for Carbon Steel in 5 M HCl Solution: Theoretical and Experimental Investigation
منشور في 2022"…The influence of Q-22 on the corrosion behavior of C-steel was elucidated using non-destructive electrochemical measurements. The overall results revealed that adding varied concentrations of Q-22 significantly decreases the corrosion rate of C-steel. …"
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The maxima in northerly wind speeds and wave heights over the Arabian Sea, the Arabian/Persian Gulf and the Red Sea derived from 40 years of ERA5 data
منشور في 2020"…We have analyzed climatology and trends of northerly maximum wind speed and significant wave height (Hs) in the Arabian Sea and the connected marginal seas, Arabian/Persian Gulf and the Red Sea, during non-monsoon season derived from 40 years of ERA5 wind and wave data, and estimated monthly, annual and decadal extreme climate and their trends. …"
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Usefulness of In-Situ Synchrotron Study on Scale Formation during CO2 Corrosion of Mild Steel: A Review
منشور في 2016"…Figure 2 shows the anodic current as a function of time in a potentiostatic test in the NaCl solution at pH 6.3 (pCO2 = 1bar) and an applied potential of ? 500 mV (vs SCE), together with the intensities of the Fe and FeCO3 signals from the in-situ synchrotron XRD [1]. …"
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