يعرض 1 - 20 نتائج من 34 نتيجة بحث عن '(( 5 a decrease ) OR ((((( _ we decrease ) OR ( 2 _ decrease ))) OR ( a non decrease ))))~', وقت الاستعلام: 0.23s تنقيح النتائج
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    A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

    منشور في 2025
    "…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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    article
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    Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

    منشور في 2025
    "…Using a systematic review of the epidemiological literature and a newly developed meta-regression tool (meta-regression: Bayesian, regularised, trimmed), we derived disease-specific, non-parametric exposure–response curves to estimate relative risk as a function of PM2·5 concentration. …"
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    article
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    Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy حسب Laiche, Djouhri

    منشور في 2020
    "…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …"
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    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

    منشور في 2019
    "…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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    Repositioning of the global epicentre of non-optimal cholesterol حسب Taddei, Cristina

    منشور في 2020
    "…Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. …"
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    Wind energy potential along the onshore and offshore Qatar حسب Mohammed, Aboobacker Valliyil

    منشور في 2020
    "…cant increase or decrease of wind power around Qatar in the last 40 years in most of the locations, while there is a slight decreasing trend in the o?…"
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    In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

    منشور في 2023
    "…Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. …"
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    Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor حسب J., Bhadra

    منشور في 2013
    "…From DSC data, it is clear that the blend film exhibits the combined physical properties of both the polymer components. The non-ohmic behavior of I–V characteristics by the blend films indicates that these nanocomposite films may have some utility in electronic device applications; an increase in conductivity is observed with decreasing PS concentration. …"
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    Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats حسب Kiss, K.

    منشور في 2016
    "…In a pilot study, EPO at 100 U/mL significantly decreased cell death compared to vehicle (33.8 ± 2.3% vs. 40.3 ± 1.5%, p < 0.05) in rat neonatal cardiomyocytes subjected to simulated ischemia/reperfusion. …"
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    Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters حسب Ayesh, Ahmad I.

    منشور في 2016
    "…Two batches of sensors were tested in this work: i) sensors based on graphene only, and ii) sensors based on graphene and percolating films of Au nanoclusters, each has a thickness of 5 nm. …"
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    Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

    منشور في 2024
    "…Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. …"
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    Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

    منشور في 2024
    "…Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. …"
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    article
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    Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 حسب Mokdad, Ali H

    منشور في 2016
    "…The crises in Egypt, Yemen, Libya, and Syria have resulted in a reduction in life expectancy; life expectancy in Syria would have been 5 years higher than that recorded for females and 6 years higher for males had the crisis not occurred. …"
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