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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
منشور في 2020"…Methodology: C57BL/6 mice (n=20) were fed with a high fat diet (60%) for 16 weeks to generate diet induced obese (DIO) mice with body weights between 45–50 gm. Thereafter, DIO mice received either SFN (5mg/kg BW) (n=10) or vehicle (n=10) as controls daily by intraperitoneal injections for four weeks. …"
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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis...
منشور في 2014"…Upon knockdown of AhR and Nrf2 the MMA(V)-, DMA(V)-, and TMA(V)-mediated induction of both CYP1A1 and NQO1 proteins was significantly decreased. …"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
منشور في 2019"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution
منشور في 1988"…The concentrations of NaNO2 employed are in the range 1-5×10-5. There is a linear relationship between the corrosion potential and the molar concentration of NaNO2. …"
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
منشور في 2019"…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …"
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Tailoring optical absorption in silicon nanostructures from UV to visible light: A TDDFT study
منشور في 2016"…(ii) The exciton binding energy is seen to decrease by approximately 45% from 0.67 eV to about 0.3 eV with length increase, for a nanostructure with a cross-section diameter of approximately 12 Å. …"
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The impact of COVID-19 pandemic on tobacco use: A population-based study
منشور في 2023"…Among the smokers, 38.5-45.8% reported a "no-change,"while 32.1-41.7% reported a "decrease"in SH during confinement. …"
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Techno-economic assessment of upfront nitrogen removal in a baseload LNG plant
منشور في 2023"…The total annual cost (TAC) and LNG energy content increased by 12.3% and 4.5% respectively over the base process. This leads to a 7.4% COE increment over the base case for 87.5% UNR. …"
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Effects of polyphenol-rich traditional herbal teas on obesity and oxidative stress in rats fed a high-fat–sugar diet
منشور في 2022"…Three herbal teas were prepared from Hibiscus rosa-sinensis flowers and Zingiber officinalis rhizomes and their mixture (3:1, respectively). Total phenolic contents (TPC) of Hibiscus rosa-sinensis and Zingiber officinalis extracts were found to be 5.82 and 1.45 mg/g of dry plant material, measured as GAE, while total flavonoid contents (TFC) were 9.17 and 1.95 mg/g of dry plant material, measured as CE, respectively. …"
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Impact of combined oil-in-water emulsions and particulate suspensions on ceramic membrane fouling and permeability recovery
منشور في 2019"…The addition of 1500 mg·L−1 of bentonite to a 10 vol.% emulsion resulted in a permeability decrease of 3.5–5 times over that recorded for the emulsion, and 8–36 times lower than that of the bentonite suspension. …"
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