Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes حسب Manjunath Ramanjaneya (14603468)

"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study حسب Brit Mollenhauer (482499)

"…<p dir="ltr">α‐Synuclein is the major component of Lewy bodies and a candidate biomarker for neurodegenerative diseases in which Lewy bodies are common, including Parkinson's disease and dementia with Lewy bodies. …"

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar حسب Lolwa Al Ansari (18466227)

"…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. Notably, there was a remarkable decrease in patients who Left Without Being Seen (LWBS) and in absconded patient rates from 2020 to 2023 (Figure 2).…"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach حسب Pavlopoulos, Kosmas

"…The geomorphological evolution of the southeastern coastal area of Farasan Al-Kabir Island (Saudi Arabia) is revealed by the mapping of modern landforms and a multi-proxy and high spatial resolution study including grain size, particulate organic carbon, mineralogy, element geochemistry, benthic foraminifera analysis and radiocarbon dating of a 3.3-m long sediment core. …"
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings حسب Khan, M.S.

"…This research aims to develop an innovative solution by incorporating AlN nanoparticles with various concentrations (0.1, 0.2, 0.4, and 0.8 g/L) as reinforcement in the Ni-P electrolyte to develop composite coatings using A36 carbon steel as a substrate through direct current (DC) electrodeposition method. …"
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings حسب M.S. Khan (22047413)

"…This research aims to develop an innovative solution by incorporating AlN nanoparticles with various concentrations (0.1, 0.2, 0.4, and 0.8 g/L) as reinforcement in the Ni-P electrolyte to develop composite coatings using A36 carbon steel as a substrate through direct current (DC) electrodeposition method. …"

Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study حسب Mona Metwally El-Sayed (17725127)

"…</p><p><br></p><h3>Results</h3><p dir="ltr">A statistically significant decrease in anxiety level among the study group compared to the control group (Pre = 16.68 (7.35), immediate = 6.65 (2.89), post three-month = 7.68 (2.75), p=<0.001 and effect size = 0.715). …"

Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar حسب John M., Rivers

"…The Khor Al Adaid embayment of southern Qatar represents a unique shallow-water mixed siliciclastic‑carbonate coastal depositional system that developed in a hyper-arid climatic setting over the past 6000 years. …"
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Microstructure and Compressive Behavior of Al–Y₂O₃ Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying حسب Manohar Reddy Mattli (18147568)

"…The microhardness first increased from 38 Hv to 81 Hv, and then decreased to 74 ± 4 Hv for 1.5 vol. % yttria. The Al–1.5 vol. % Y₂O₃ nanocomposite exhibited the best ultimate compressive strength and yielded a strength of 359 ± 7 and 111 ± 5 MPa, respectively. …"

Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review حسب Hamid El Bilali (15864930)

"…<p dir="ltr">Amid Ukraine’s geopolitical turmoil, a ripple effect is echoing across global agricultural and food systems – a phenomenon with far-reaching implications for producers, traders, and consumers across the globe. …"