بدائل البحث:
_ stable » _ state (توسيع البحث)
_ best » _ west (توسيع البحث), _ test (توسيع البحث), _ breast (توسيع البحث)
a el » a al (توسيع البحث), _ el (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
_ stable » _ state (توسيع البحث)
_ best » _ west (توسيع البحث), _ test (توسيع البحث), _ breast (توسيع البحث)
a el » a al (توسيع البحث), _ el (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">The use of gentamicin in the treatment of infectious diseases requires frequent monitoring to attain the best treatment outcomes.</p><h3>Objective</h3><p dir="ltr">This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar.…"
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
منشور في 2022"…<h2>Purpose</h2> <p>The study aims to prospectively compare double and triple arthrodesis in terms of functional outcomes and deformity correction. To the best of our knowledge, this is the first prospective comparative study in the literature to date.…"
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