Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. Results. Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes حسب Muhammad Danyal Ahsan (14488278)

"…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar, Shurbaji

"…BackgroundIn the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …"
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Pilot testing of a novel Multi Effect Distillation (MED) technology for seawater desalination حسب Shahzada Aly (17191465)

"…By implementing this invention's design, the heat transfer area has been decreased and accordingly, the capital cost of the evaporator is reduced by 20%. …"

Nickel toxicology testing in alternative specimen from farm ruminants in a urban polluted environment حسب Zafar Iqbal Khan (21225059)

Corrosion Evaluation of 316L Stainless Steel Exposed to CNT-Water Nanofluid حسب Dana Abdeen (18147583)

"…Three consequent corrosion tests were conducted on 316L stainless steel (SS) exposed to carbon nanotubes (CNTs) water-based nanofluids: open circuit test, polarization resistance test, and potentiodynamic scans. …"

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…Significantly changed FA and MD values in different brain regions in HIC and HUC compared to CHNM were used for correlation analysis with NP test scores using Pearson’s correlation. ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …"
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review حسب Sunji, Nadine

"…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). …"
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Engineering Novel Single-chain Variable Fragments for Therapeutic and Diagnostic Approaches in Parkinson's Disease حسب Safa Salim (9186786)

"…Furthermore, the scFvs decreased α-synuclein seed-induced toxicity in a cell model of PD. …"

Stability and thermophysical properties test of carbide-derived carbon thermal fluid; a comparison between functionalized and emulsified suspensions حسب Ismail W. Almanassra (14151321)

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar Shurbaji (9938696)

"…<h3>Background </h3><p dir="ltr">In the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …"

Drive‐up INR testing and phone‐based consultations service during COVID‐19 pandemic in a pharmacist‐lead anticoagulation clinic in Qatar: Monitoring, clinical, resource utilization... حسب Eman N. Alhmoud (14778706)

"…Combined with teleclinics, using drive-up fingerstick International normalized ratio (INR) testing was recommended to decrease exposure risk of anticoagulation patients.…"

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training حسب Georges Jabbour (754884)

"…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O₂ (r = 0.61, p < 0.01). …"

A Case Study to Identify the Hindrances to Widespread Adoption of Electric Vehicles in Qatar حسب Amith Khandakar (14151981)

"…<p dir="ltr">The adoption of electric vehicles (EVs) have proven to be a crucial factor to decreasing the emission of greenhouse gases (GHG) into the atmosphere. …"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis حسب Wouter Hendrickx (44559)

"…The mutation and neoantigen load progressively decreased from ICR4 to ICR1 but could not fully explain immune phenotypic differences. …"

Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment حسب Minier-Matar, Joel

"…Bench-scale operational and water quality results were comparable to the full-scale RO performance data validating the lab testing procedure implemented in this study.…"
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Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study حسب Brit Mollenhauer (482499)