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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…To this end, we used anonymized internet search engine data to investigate which medical conditions and symptoms preceded searches for 12-step meeting locators and general 12-step information.…"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Global gene expression profiling was conducted using the Agilent microarray platform, and data normalization and bioinformatics were performed using GeneSpring software. …"
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…Here we show that hippuristanol, a compound that impedes eIF4A in a manner distinct from PatA, similarly inhibits the iNOS/NO pathway and cytokine-induced muscle wasting. …"
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Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation
منشور في 2022"…We describe our differentially-private model with flexible constraints and a dynamic window algorithm to maintain the privacy-budget loss in infinitely generated time-series data. Our experimental results show a possible decrease in data perturbation error by 51.7% and 61.2% for smart meters and fog-computing data aggregators perturbed data, respectively, compared to the commonly used Gaussian mechanism.…"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene
منشور في 2023"…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…"
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Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
منشور في 2024"…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO<sub>2</sub> column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO<sub>2</sub> levels before, during and after the tournament over Greater Doha. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Persona Transparency: Analyzing the Impact of Explanations on Perceptions of Data-Driven Personas
منشور في 2019"…This finding suggests that explaining the algorithmic process of data-driven persona creation involves a “transparency trade-off”. …"
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Machine Learning and Carbonate Reservoirs : A Production Data Perspective on Permeability Modelling
منشور في 2024"…It was noted that in cases where permeability increases from one well to another, the production data showed a decrease. Removing these producers from the training dataset led to an 10% decrease in ANN performance, highlighting their importance in capturing the non-linear relationship between permeability and production data.…"
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On-site workshop investment problem: A novel mathematical approach and solution procedure
منشور في 2023"…These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. …"
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Using artificially generated pictures in customer-facing systems: an evaluation study with data-driven personas
منشور في 2020"…Based on 496 participants using 4 persona treatments (2 × 2 research design), findings of Bayesian analysis show that using the artificial pictures in persona profiles did not decrease the scores for Authenticity, Clarity, Empathy, and Willingness to Use of the data-driven personas.…"
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Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
منشور في 2020"…Continually increasing the insitu and remote sensing data sizes, spatially and temporally, defines a long-term priority.…"
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