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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte.
منشور في 2018"…The differentiation medium, containing cAMP, PDGFA, T3, and all-trans-retinoic acid (ATRA), promotes OBNSCs to generate mostly oligodendrocytes (OLs) displaying morphological changes, and appearance of long cytoplasmic processes. OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …"
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Mercury pollution in doha (Qatar) coastal environment
منشور في 1994"…Dissolved reactive Hg (2.9 ng L?1) represented 81.0% of the total dissolved Hg (3.5 ng L?…"
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Effect of Hyperglycemia on eNOS function in EPCs
منشور في 2020"…Cells were treated with normal glucose (NG, 5.5mM) and high glucose (HG, 25mM) media for 3 & 6 days, and the effect on eNOS and Akt phosphorylation were assessed using western blot. …"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …"
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RIGOROUS SIMULATION AND OPTIMIZATION OF THE COLD SECTION IN A REAL LNG PLANT: UPFRONT NITROGEN REMOVAL AS PROCESS ENHANCING CONCEPT
منشور في 2023"…UNrem of 87.5% scenarios showed a profit of 24.2 billion USD in 20 years. …"
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INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS
منشور في 2015"…Large piece-to-piece variations of contamination up to two orders of magnitude were discovered within sites (2 to 1,005 ng/g), although there was no significant difference in contaminant concentration among all sites for PCBs and PAHs respectively. …"
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Investigation of Spatiotemporal Variability of Microplastics in Qatar's Cstal Environment
منشور في 2016"…Large piece-to-piece variations of contamination up to two orders of magnitude were discovered within sites (2 to 1,005 ng/g), although there was no significant difference in contaminant concentration among all sites for PCBs and PAHs respectively. …"
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
منشور في 2024"…These factors included 2.5nM tumor necrosis factor-alpha (TNFα), 20 ng/ml interleukin-6 (IL-6), 10 micromole 4-hydroxynonenal (4HNE), and high insulin (HI) at a concentration of 100nM. …"
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
منشور في 2020"…Furthermore, SFN treatment did not significantly affect the systemic insulin (1.84±0.74 vs 1.54±0.55 ng/ml, p=0.436), or adiponectin (11.96 ±2.29 vs 14.4±3.33 ug/ml, p=0.551) levels in SFN vs. vehicle-treated DIO mice, respectively. …"
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