Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis حسب Maria K. Smatti (4675852)

"…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…"

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…The upregulation of 40S ribosomal protein S9 (3-fold), 40S ribosomal protein S15 (4.2-fold), 40S ribosomal protein S18 (2.5-fold), and 60S ribosomal protein L22 (4.4-fold) implied the induction of translation machinery. …"

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma Younes (6424865)

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"

Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers حسب Mostafa Shibl (18810412)

"…LSTM provided the best results with an accuracy of 95% for predicting the most appropriate power rating (PR) for EVCS, followed by RF, DT, DNN, SVM, KNN, and NB. Additionally, LSTM was also the model with the smallest error rate, at a value of ±0.7%, followed by RF, DT, KNN, SVM, DNN, and NB. …"

Vocal Changes in Patients With Polycystic Ovary Syndrome حسب Hannoun, Antoine

"…In the control group, one subject had vocal fold edema and one subject had vocal fold nodules. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet حسب Bassil, Maya

"…Results The intake of S. libanotica extract was associated with a significant decrease in fasting serum glucose (102.9 ± 10.8 in GII and 87.5 ± 6.4 in GIII vs. 152.1 ± 7.9 mg/dl in controls) and a two fold increase in fasting serum insulin (GIII) and liver glycogen content (GII and GIII). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hygienic quality of chlorinated city water stored in household tanks in Byblos, Lebanon. (c2004) حسب Abi Chedid, Najib

احصل على النص الكامل
احصل على النص الكامل

Qatar’s immigrants at higher risk of diabetes حسب Nature Research (16552612)

"…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …"

Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions حسب Vryzas, Zisis

"…The yield stress increased linearly with temperature by almost three-fold, the flow consistency index decreased exponentially with temperature by almost five-fold and the flow behavior index increased by about 20%, tending towards the Newtonian value. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis حسب Meritxell Espino‐Guarch (22565774)

"…The absence of LAT2 led to increased intramuscular glutamine (Gln) accumulation (6.3‐fold, <i>p</i> < 0.0001), accompanied by a reduction in skeletal muscle proteolysis during fasting (0.61‐fold, <i>p</i> = 0.0004) primarily due to decreased proteasomal and autophagic activity (0.45‐fold, <i>p</i> = 0.016 and 0.7‐fold, <i>p</i> = 0.002, respectively). …"

Zirconium phytate-based proton conductors for high-temperature fuel cell applications حسب Nimir, Wessam Ahmed Mohamed

احصل على النص الكامل

Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines حسب Ismail, Jana

"…Thus, according to Drug Reduction Index (DRI), a combination of 6-fold less concentration of cisplatin with 1.3-fold less concentration of CBD yields a 95% cell growth inhibition. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis حسب Milane, Aline

"…Consistent with this, P-gp function was also increased by 1.5-fold and riluzole brain disposition was decreased by 1.7-fold in mSOD1 mice. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine حسب Debendra Muduli (20748758)

"…The effectiveness has been evaluated using two standard datasets called G1020 and ORIGA with the $$10 \times 5$$-fold stratified cross-validation technique to ensure reliable evaluation. …"

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis حسب Charbel Abi Khalil (14150028)

"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"

Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients حسب Bouquet, Antoine

"…The main limitation of this strategy is that it can be offered only in selected patients with synchronous disease,5, 6, 7, 8, 9 and 10 and it is associated with an increased risk of postoperative complications when major liver resection is combined with resection of the primary tumor.11, 12 and 13 Recently, a “reverse strategy,” in which preoperative chemotherapy is followed by resection of the CLM and then by resection of the colorectal primary at a second operation, has been proposed for patients with advanced synchronous CLM, and in particular, for patients in whom the primary is located in the rectum.14 The rationale for the reverse strategy is 2-fold: primary-related complications (such as bleeding, obstruction, or perforation) are rare in patients with stage IV colorectal cancer receiving combination chemotherapy15 and 16 and treatment of the metastatic disease is not delayed by local therapy for the primary tumor (surgery, and in the case of rectal cancer, radiotherapy or radiochemotherapy) or by complications of surgical treatment of the primary tumor. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Processing Effects on the Oxytetracycline and Tylosin Antibiotic Residues in Middle Eastern Dairy Products حسب Saidy, Liz

"…Curding step had a significant (p=0.028) effect on OTC only with the concentration increasing by almost 1.5 folds. Acidification and heating of whey to produce Double Cream decreased significantly (p=0.037) OTC concentration by 14.7 to 46.3%, while TYL concentration increased significantly (p=0.000) by 300%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل