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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
منشور في 2024"…This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …"
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3
Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
منشور في 2022"…Significant differences included various frequency domain and nonlinear HRV parameters, particularly between first and fourth HN quintiles with p values < 0.001 for recurrence plot analysis (RPA), detrended fluctuation analysis (DFA) a1 and Poincaré plot ratio SD1/SD2. The results revealed non-monotonic relationships between measures of HRV and HN concentration. …"
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4
Non-linear relationship between real commodity price volatility and real effective exchange rate: The case of commodity-exporting countries
منشور في 2019"…Our results highlight that the relationship between real commodity price volatility and REER is non-linear and depends on the degree of financialization of the commodity market. …"
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5
Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…Vitamin D deficiency has been linked to increased adiposity and decreased bone density. It is not known if vitamin D is linked to adiposity measures and bone mass in postmenopausal Qatar women. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
منشور في 2016"…The pH range for the Clinoleic formulations (7.1–7.5) was slightly higher than that of the Intralipid formulations (6.5–6.9). …"
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9
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
منشور في 2021"…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
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10
Dispatchable capacity optimization strategy for battery swapping and charging station aggregators to participate in grid operations
منشور في 2023"…Extensive simulations and numerical results show that the BSCS aggregator with demand-side regulation capacity can increase its income by 59.05% and 36.78% on working and non-working days, respectively. Also, the aggregator does not worsen the original power load while meeting the EV swapping demand and can decrease the daily load fluctuations by 0.65% and 12.89%, reduce the peak–valley difference by 5.81% and 7.80%, and increase the load rate by 3.67% and 4.08% in working and non-working day situations through providing the dynamic dispatchable capacity for the grid.…"
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
منشور في 2023"…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. …"
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Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
منشور في 2023"…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …"
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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
منشور في 2024"…Furthermore, Wilcoxon and Friedman's non-parametric tests were accomplished to support the performance of the proposed method.…"
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…The global all-age incidence rate of URIs decreased by 10·1% (–12·0 to –8·1) from 1990 to 2019. …"
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…The age-standardized incidence rate (ASIR) of all cancers combined in Asia was 197.6/100,000 [181.0–214.4] in 2019, varying from 99.2/100,000 [76.1–126.0] in Bangladesh to 330.5/100,000 [298.5–365.8] in Cyprus. The age-standardized mortality rate (ASMR) was 120.6/100,000 [110.1–130.7] in 2019, varying 4-folds across countries from 71.0/100,000 [59.9–83.5] in Kuwait to 284.2/100,000 [229.2–352.3] in Mongolia. …"
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16
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…CD and DLS analyses showed that proteins from HP-treated teeth mostly adopted a non-random conformation and had smaller average protein sizes compared to the control. …"
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Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050
منشور في 2024"…FindingsMore adolescents and young adults were expected to develop MSK disorders by 2050. Across five age groups, the rates of prevalence, YLDs, and DALYs for RA, NP, LBP, gout, and OMSKDs sharply increased from ages 15–19 to 35–39; however, these were negligible for OA before age 30 but increased notably at ages 30–34, rising at least 6-fold by 35–39. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …"
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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
منشور في 2024"…Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). …"
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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
منشور في 2016"…Most increases in DALYs, especially from non-communicable diseases, were due to population growth. …"
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