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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
منشور في 2024"…<h3>Background</h3><p dir="ltr">Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. …"
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Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform
منشور في 2024"…This revealed clustering of S1-RBD on membrane and more importantly, a depletion of the Omicron S1-RBD from membrane corrals, which was not seen with the WT S1-RBD. …"
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Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing <i>via</i> stereolithography
منشور في 2025"…Notably, pure PMMA exhibited the highest tensile strength, 26.23 ± 0.14 MPa and an elastic modulus of 707.81 MPa, while PMMA resin/1% Mg showed the lowest strength (19.46 ± 0.25 MPa) and modulus (392.88 MPa), indicating a decrease in mechanical integrity with higher Mg content. …"
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SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
منشور في 2024"…We analyzed ADCC activity targeting SARS‐CoV‐2 spike (S) and nucleocapsid (N) proteins in convalescent sera following WT SARS‐CoV‐2‐infection (<i>n</i> = 91), including symptomatic and asymptomatic infections, omicron‐infection (<i>n</i> = 8), COVID‐19 vaccination with messenger RNA‐ (mRNA)‐ (BNT162b2 or mRNA‐1273, <i>n</i> = 77), adenovirus vector‐ (<i>n</i> = 41), and inactivated virus‐ (<i>n</i> = 46) based vaccines, as well as post‐mRNA vaccination BTI caused by omicron (<i>n</i> = 28). …"
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…To characterise the impact on muscle degradation, we tested LAT2 KO mice in cancer‐associated cachexia, streptozocin‐induced Type‐1 diabetes, and ageing models.</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …"
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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit
منشور في 2024"…</p><h3>Objective</h3><p dir="ltr">This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar.</p><h3>Methods</h3><p dir="ltr">A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"
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Ultra-low thermal conductivity in scheelite and A-deficient scheelite ceramics
منشور في 2021"…BaMoO ceramic has shown a decrease in thermal conductivity from 0.8 W m K to 0.65 W m K from 400 K to 650 K. …"
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Sleeping habits during COVID-19 induced confinement: A study from Jordan
منشور في 2021"…Majority of the participants (53–59%) reported an increase in most of the sleep parameters except a decrease (49.1%) in daytime sleep. …"
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…We aimed to describe the epidemiological and clinical characteristics of fall-related injuries in a level 1 trauma center.</p> <h2>Method</h2> <p>A retrospective analysis of Qatar Trauma Registry data was conducted on patients admitted for fall-related injuries between 2010 and 2017. …"
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Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 825 participants with mean age 29.2 years (5.9) of which 365 (44.2%) were males. …"
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Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country
منشور في 2022"…We sought to determine these in a large cohort of critically ill COVID-19 patients in Qatar and explore the early mortality predictors. …"
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Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…AC, TT, ST, and PT are all associated with decreased odds of death from SPE.</p><h2>Other Information</h2><p dir="ltr">Published in: Thrombosis Research<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.thromres.2022.07.013" target="_blank">https://dx.doi.org/10.1016/j.thromres.2022.07.013</a></p>…"
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Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study
منشور في 2022"…There was an increase in olive oil (9% vs. 12%; p < 0.001), vegetables (54.3% vs. 58.7%; p = 0.005), legumes (11.8% vs. 15.3%; p = 0.007), sofrito (70.9% vs. 77.3%; p < 0.001) and fat (45.9% vs. 53.8%; p < 0.001) consumption and a decrease in fresh fruit (39.4% vs. 15.8%; p < 0.001) and fish/seafood (5.9% vs. 3.9%; p = 0.0035) consumption during lockdown. …"
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Diffusion tensor imaging with tractography in surgical resection of brainstem cavernous malformations: a systematic review and meta-analysis
منشور في 2023"…The utilization of preoperative diffusion tensor imaging significantly increased the proportion of improved patients and decreased the proportion of worsened patients. However, further controlled research is needed to draw a definite conclusion about the usefulness of its role.…"
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Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
منشور في 2024"…</p><h2>Other Information</h2><p dir="ltr">Published in: The American Journal of Emergency Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.ajem.2024.05.010" target="_blank">https://dx.doi.org/10.1016/j.ajem.2024.05.010</a></p>…"
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…BackgroundCancers represent a challenging public health threat in Asia. This study examines the temporal patterns of incidence, mortality, disability and risk factors of 29 cancers in Asia in the last three decades. …"
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Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial
منشور في 2017"…<h3>Background</h3><p dir="ltr">Improving mobility in elderly persons is a primary goal in geriatric rehabilitation. Self-regulated exercises with instruction leaflets are used to increase training volume but adherence is often low. …"
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Thermodynamic Analysis of Gravity Assisted Solar-Powered Reverse Osmosis Unit for Greenhouses Situated in a Depleted Zone with Performance Evaluation and Improvements Using Nanoflu...
منشور في 2021"…<p dir="ltr">The Sabkha-Tah region of Western Sahara is a location where adverse weather conditions make it difficult for certain crops' conventional farming. …"
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Future fertility rates were projected to continue to decline worldwide, reaching a global TFR of 1·83 (1·59–2·08) in 2050 and 1·59 (1·25–1·96) in 2100 under the reference scenario. …"
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