Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. حسب Seidel, Monika

"…The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. …"
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Dynamic workload patterns prediction for proactive auto-scaling of web applications حسب Iqbal W.

"…The framework is implemented and experimentally evaluated using historical access logs of three real web applications, each with increasing, decreasing, periodic, and randomly varying arrival rate behaviors. …"
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Decreased soil moisture due to warming drives phylogenetic diversity and community transitions in the tundra حسب Scharn, Ruud

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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and... حسب Emna, Djebbi

"…The most resistant life stage was N1 with LC50 values > 1500 μg L-1 and >5000 μg L-1, respectively for E2 and EE2. …"
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Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract حسب Ahmed, Rashid

"…The DPPH assay demonstrated a higher antioxidant potential (IC-50 value of 133 μg/ml), which was comparable to the IC-50 of ascorbic acid (122.4 μg/ml). …"
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Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model حسب Zakaria, Zain Z

"…Our data showed that AuNRs caused mortality with a calculated LC50 of EC50,24hpf of AuNRs being 9.1 μg/mL, while a higher concentration of AuNRs was revealed to elicit developmental abnormalities. …"
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics حسب Nomikos, Michail

"…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …"
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Evaluation of Apoptotic, Antiproliferative, and Antimigratory Activity of Origanum syriacum against Metastatic Colon Cancer Cells حسب Aldisi S.S.

"…OSEE showed a concentration-dependent apoptotic and antiproliferative effect on LoVo and SW620 cells at 500 μg mL−1 or higher after 48 h of exposure. Additionally, OSEE inhibited the migration of both LoVo and SW620 cells by decreasing (50–75%) wound-healing capacity at 500 and 1,000 μg mL−1. …"
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In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy حسب AlanaziR.

"…Results In both term-pregnant and non-pregnant uterine strips, H 2 O 2 elicited a biphasic response, consisting of a transient contraction followed by a persistent decrease in spontaneously generated contractions, contractions induced by oxytocin, and contractions induced by high Ca +2 (all P< 0.01, compared with controls) in a concentration-dependent manner. …"
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Selection of Bacillus spp. with decontamination potential on multiple Fusarium mycotoxins حسب Zahoor Ul, Hassan

"…Complete degradation (100%) of ZEN was observed at a contamination level of 0.375 μg/ml in LB, while showing a decreasing trend of degradation (87 and 84%) at increasing levels of mycotoxins (0.750 and 1.50 μg/ml LB medium, respectively). …"
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Possible Ionic Effects of NaCl on Two Mexican Wheat Cultivars حسب Yasseen, B.T. [بسام طه ياسين]

"…The ionic agents, NaCl and Na2SO+, decreased K* and Ca2* in the leaves, while PEG had little effect on leaf iontent of r* ana- Ca2i lif in.r. ug"",t increased phosphorus in leaves of both cultivars, but PEG had the smallest effect. …"
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The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis حسب Jamialahmadi, Tannaz

"…This meta-analysis aimed to provide an answer as to whether statins do affect decreasing the plasma levels of atherogenic TMAO. Methods A systematic literature search in PubMed, Scopus, Embase, and Web of Science was performed from inception to January 1st, 2023. …"
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Da'as, Sahar I.

"…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …"
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Osteoporosis in patients with stroke: A cross-sectional study حسب Tomasevic-Todorovic, Snezana

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Global patterns and predictions of seafloor biomass using random forests حسب Wei, C.-L.

"…Lowest values are consistently encountered on the central abyssal plains of major ocean basins The shift of biomass dominance groups with depth is shown to be affected by the decrease in average body size rather than abundance, presumably due to decrease in quantity and quality of food supply. …"
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Effects of supervisor’s personality on the support, abuse, and feedback provided to junior accountants حسب Saadullah, Shahriar M.

"…Methodology/approach – We conducted a web-based study with 115 accountants from a top 100 US accounting firm. …"
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A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department حسب Losier, Mia

"…Where identified, benefits of AMS interventions primarily included improvement in delivery of care or a decrease in antimicrobial utilization; however, most studies were rated as having unclear or high risk of bias. …"
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INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS حسب Abayomi, Oyebamiji Abib

"…Microplastics pose greater threats as they can be mistaken for food by filter-feeders and planktivorous fish, and can also adsorb large quantities of recalcitrant organic pollutants (OPs) which biomagnify up the marine food web, hence, explains the need for their investigation. …"
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