Decreased phosphodiesterase activities in cardiac hypertrophy حسب Abi-Gerges, A.

"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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A study to identify and evaluate the decreased interest in mime in Lebanese society. (c1982) حسب Radwan, Nada

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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains حسب Abuzaid, Wael

"…This paper is dedicated to study the heterogeneity in the total and transformation strains of the high temperature shape memory alloy Ni50.3Ti25Hf24.7 subjected to fatigue loading and aims to provide further insight to the source of transformation strain instability. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model حسب Halema Al-Kandari (6316961)

"…For the RGOTi, the no observed effect concentration (NOEC, mortality/teratogenicity score <20%) and the median lethal concentration (LC₅₀) were <400 and 748.6 mg/L, respectively. …"

β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo حسب Daaboul, Hamid E.

"…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …"
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis حسب Daaboul, Hamid E.

"…It also significantly decreased the levels of pro-caspase-3, p53, Bcl-2, p-Erk/Erk and p-Akt/Akt and increased p21 and Bax proteins. …"
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways حسب Daaboul, Hamid E.

"…HC showed a dose-dependent decrease in cell survival with an IC50 of 18 and 14.5 μg/ml after 24 and 48 h respectively. …"
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Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer حسب Shebaby, Wassim N.

"…Additionally, F2 fraction treatment caused an up-regulation of the expression of pro-apoptotic (Bax) and down-regulation of the expression of anti-apoptotic (Bcl2) proteins. A decrease in the phosphorylation of AKT and ERK was also observed. …"
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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress حسب Houbeika, Rouba

"…A decrease in the hippocampal p-Akt protein levels is observed in depressed subjects. …"
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis حسب Mroueh, MA

"…We treated the cells with PF and performed western blots looking at p-Akt and p-ERK. We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes حسب Fakhoury, H.

"…Expression of GLUT1, GLUT4, PIP3, pAkt, pPTEN, and PARK-7 was examined by western blot. …"
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
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Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress حسب Munazza T. Fatima (17280679)

"…Importantly, SESN2 silencing, unlike thapsigargin, caused a dramatic decrease in protein expression and phosphorylation of Akt, a critical pro-survival hub and component of the AMPK/Akt/mTORC1 axis. …"

Metformin treatment inhibits motility and invasion of glioblastoma cancer cells حسب Al Hassan, Marwa

"…The results show a significant decrease in the survival of SF268 cancer cells in response to treatment with metformin. …"
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Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells حسب Zgheib, Perla

"…The present study aims to investigate the effect of the most potent DC fraction, pentane/diethyl ether (50:50), on lung, skin, breast and glioblastoma cancer cell motility and invasion. …"
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Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma حسب AbouAntoun, Thamara Jihad

"…PDGF-BB treatment of cells enhanced migration and proliferation after 24 hr; increased PDGFRβ, PI3K, Akt and Erk1/2 activity, decreased PTEN activation and transactivated EGFR. …"
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models حسب Al Toufaily, Sahar

"…On the other hand, treatment with HC (50 mg/kg) or DCOE (100mg/kg) demonstrated significant decrease in serum urea, but little or no effects was observed on serum creatinine. …"
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