Decreased phosphodiesterase activities in cardiac hypertrophy حسب Abi-Gerges, A.

"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

A study to identify and evaluate the decreased interest in mime in Lebanese society. (c1982) حسب Radwan, Nada

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β-2-himachalen-6-ol حسب Taleb, Robin I.

"…GC–MS and NMR spectroscopy revealed the identity of the major compound as β-2-himachalen-6-ol, a novel sesquiterpene unique to the Lebanese wild carrot. β-2-Himachalen-6-ol demonstrated potent anti-cancer activity against B16F-10, Caco-2, MB-MDA-231, A549 and SF-268 cancer cells (IC50 13–4 µg/ml; 58–18 µM), with SF-268 cells being the most sensitive. …"
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Stemming cardiovascular diseases in Qatar حسب Nature Research (16552612)

Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains حسب Abuzaid, Wael

"…No homogenization of the transformation strain field was observed as a result of either stress increase or thermal cycling. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis حسب Daaboul, Hamid E.

"…Papilloma yield, volume, histology, and mice weight and liver function were assessed. HC treatment decreased significantly cell survival (IC50 = 7 and IC90 = 40 μg/ml) and increased significantly cells undergoing late apoptosis and necrosis. …"
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …"

β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo حسب Daaboul, Hamid E.

"…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …"

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
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Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties حسب Slimani, Ahmed

"…The lead-free Na 0.5 Bi 0.5 0.94 Ba 0.06 TiO 3 (NBT-6BT) ceramics was fabricated at various sintering temperatures using a conventional solid-state reaction method. …"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model حسب Halema Al-Kandari (6316961)

"…H₂RGOTi showed a NOEC similar to RGOTi. However, no significant mortality was detected at all concentrations used in the acutoxicity assay (up to1000 mg/L), thus indicating a hypothetical LC₅₀ higher than 1000 mg/L. …"

STEM: spatial speech separation using twin-delayed DDPG reinforcement learning and expectation maximization حسب Muhammad Salman Khan (7202543)

"…Additionally, it reduces the required training data by 39 times, training time by 36 times, model size by 6 times, real time factor (RTF) by 1 point, and multiply-accumulate operations (MACs) by 9 times compared to a recently proposed lightweight transformer-based encoder-decoder framework, while offering a slight decrease in PESQ score (by 0.45 points).…"

The effect of IL-1RA and IL-13 on cutaneous leishmaniasis in BALB/C mice as to hyperalgesia and the levels of IL-1b and IL-6. (c2005) حسب Hamdan, Hamdan Ghazi

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The anti-cancer activity of 2 himachalene-6-OL extracted from daucus carota SSP. carota. (c2014) حسب Najm, Paul I.

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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways حسب Daaboul, Hamid E.

"…Blood samples were collected for assessment of liver toxicity and colon tumor incidence and size were studied histologically. HC showed a dose-dependent decrease in cell survival with an IC50 of 18 and 14.5 μg/ml after 24 and 48 h respectively. …"
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