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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"
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Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
منشور في 2017"…The cytotoxic effect of fractions (10, 25, 50 and 100 μg/mL) was tested on human epidermal keratinocytes (non-tumorigenic HaCaT cells and tumorigenic HaCaT-ras variants) using WST a ssay. …"
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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains
منشور في 2017"…This paper is dedicated to study the heterogeneity in the total and transformation strains of the high temperature shape memory alloy Ni50.3Ti25Hf24.7 subjected to fatigue loading and aims to provide further insight to the source of transformation strain instability. …"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
منشور في 2019"…For the RGOTi, the no observed effect concentration (NOEC, mortality/teratogenicity score <20%) and the median lethal concentration (LC<sub>50</sub>) were <400 and 748.6 mg/L, respectively. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Antioxidant and hepatoprotective activities of the oil fractions from wild carrot (Daucus carota ssp. carota)
منشور في 2015"…The sesquiterpene-rich fraction F1 had the highest FIC ability (IC50 = 0.28 mg/ml). Pretreatment with F1 and F4 reversed the CCl4-induced decrease in SOD, CAT, and GST levels and reduced significantly hepatic damage. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …"
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
منشور في 2018"…Papilloma yield, volume, histology, and mice weight and liver function were assessed. HC treatment decreased significantly cell survival (IC50 = 7 and IC90 = 40 μg/ml) and increased significantly cells undergoing late apoptosis and necrosis. …"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …"
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Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
منشور في 2015"…The present study aims to investigate the effect of the most potent DC fraction, pentane/diethyl ether (50:50), on lung, skin, breast and glioblastoma cancer cell motility and invasion. …"
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Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma
منشور في 2023"…Intraperitoneal treatment of mice with COE (10, 25 or 50 mg/kg; 9 weeks) showed a non-significant decrease in tumor volume with respect to control, without adverse effects on liver and kidney function. …"
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …"
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