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Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
منشور في 2015"…We have intercrossed Mmp8-null mice with the Polyoma virus middle T oncogene-driven (MMTV-PyMT) mouse model of mammary cancer to explore the effects of loss of MMP-8 on the incidence and progression of mammary carcinomas. …"
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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
منشور في 2021"…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …"
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …"
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
منشور في 2024"…Laparoscopic cholecystectomy was the most common surgical approach (76.7%), particularly in type 1 (79.6%), and decreased to 50% in advanced types. Hepaticojejunostomy was more common in the advanced types.…"
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
منشور في 2022"…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …"
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Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review
منشور في 2024"…Utilizing a rigourous methodology, we screened 236 articles from the Web of Science database as of March 2023, narrowing the corpus to 62 significant publications that meet comprehensive eligibility criteria. …"
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Exponential Particle Swarm Optimization for Global Optimization
منشور في 2022"…Particle Swarm Optimization (PSO) is one of the most famous nature-inspired algorithms owing to its simplicity and ability to be used in a wide range of applications. …"
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Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study
منشور في 2018"…Pilot data on an immunoprecipitation mass spectrometry (IP‐MS) method is also presented. Our results suggest that the four immunochemical methods and the IP‐MS method measure similar forms of α‐synuclein and that a common reference material would allow harmonization of results between immunoassays.…"
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Social Network Analysis for Precise Friend Suggestion for Twitter by Associating Multiple Networks Using ML
منشور في 2022"…This approach is by and large used to decrease the dimensionality of the information alongside its feature space. …"
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Effect of UV Ageing on the fatigue life of bulk polyethylene
منشور في 2018"…The results show an important decrease of the fatigue limit with increasing absorbed UV irradiation dose.…"
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A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering
منشور في 2023"…Our model explained presences and absences of 175 plant species in 608 plots with >87% cross-validated accuracy, predicted decreases in <i>α, β</i>, and <i>γ</i> diversity by 2040 under both moderate and extreme climate scenarios, and identified likely advantaged and disadvantaged plant species under climate change. …"
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Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems
منشور في 2023"…The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …"
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
منشور في 2025"…We conducted a comprehensive search of PubMed, Web of Science, and Cochrane CENTRAL electronic databases for clinical trials comparing the use of lidocaine versus placebo, or no intervention for TCR prevention during cranial surgeries up until 20 May 2024. …"
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Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
منشور في 2022"…PubMed, Scopus, Science Direct, Web of Science, Cochrane, and LILACS were searched up to October 2021. …"
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…CO2 is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO2 to 464 μatm, similar to that observed. …"
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Excess pCO<sub>2</sub> and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…CO<sub>2</sub> is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO<sub>2</sub> to 464 μatm, similar to that observed. …"
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Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis
منشور في 2025"…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). …"