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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
منشور في 2023"…Therefore, in this study, we evaluated the risk of stroke among patients with LVT undergoing CAG +/− PCI.…"
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Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
منشور في 2017"…Superconducting transition temperature (Tc) increases up to 117.5 for x = 0.25 wt.% and then it decreases with further x addition. …"
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conferenceObject -
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
منشور في 2021"…However, β2-AR receptors expression remained unchanged regardless of the disease stage. Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …"
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What we do not know, hardly know, and really know about traffic safety
منشور في 2015"…This has never been, nor ever can be, experimentally examined. Likewise, we have no direct experimental investigation of how a driver’s crash risk increases with increasing speed. …"
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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains
منشور في 2017"…No homogenization of the transformation strain field was observed as a result of either stress increase or thermal cycling. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"
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SARS-CoV-2 Variants in Lebanon
منشور في 2024"…Genomes were generated using the artic nCoV-2019 bioinformatics protocol. We detected 53 Omicron subvariants, with XBB.1.5 (17.59%), XBB.1.42 (10.05%), and XBB.1.42.1 (9.05%), being the most common. …"
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
منشور في 2010"…Expression and functionality of P-glycoprotein (ABCB1, P-gp) and Breast Cancer Resistance Protein (ABCG2, BCRP), two major efflux pumps, were studied. We observed an increased P-gp expression (1.5-fold) in presymptomatic mSOD1 mice compared to wild-type controls. …"
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Phosphorus supplementation increases thermic response to glucose solution in healthy lean subjects
منشور في 2013"…Addition of P was associated with higher increase in VO2 (959±315 vs. 534±274 mL/60min; p= 0.03) which corresponded to higher TEF (5.7±1.6 vs. 3.6and±1.3kcal/60min; p=0.03 equivalent to 8% vs. 5% increase from RMR) during the first 60 min. …"
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Surface microenvironment engineering of black V<sub>2</sub>O<sub>5</sub> nanostructures for visible light photodegradation of methylene blue
منشور في 2021"…<p dir="ltr">Utilization of photocatalysis as a promising strategy for environmental and energy applications has been widely considered. Herein, we report a novel black V<sub>2</sub>O<sub>5</sub> material (bV<sub>2</sub>O<sub>5</sub>) synthesized using a controllable and environmentally benign physicochemical reduction method. …"
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Exploring the epigenetic landscape: The role of 5-hydroxymethylcytosine in neurodevelopmental disorders
منشور في 2024"…Moreover, we explore the implications of these findings for the development of epigenetic therapies aimed at modulating 5hmC levels. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…PLA and WE43 composite filaments, containing various magnesium concentrations (5 %, 10 %, and 15 %), were produced using solvent evaporation and extrusion methods. …"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"