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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
منشور في 2023"…We report the impact of dysprosium (Dy, with y = 0.01, 0.02, 0.05 and 0.08) substitution in (Na0.5 Bi0.5)0.94 Ba0.06TiO3 (NBT-6BT) lead-free ceramics. …"
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3
Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…We measured the levels of neutralizing total antibodies (NtAbs), anti-S-RBD IgG, and anti-S1 IgA titers among VN and NI up to ∼10 months from administration of the first dose, and up to ∼7 months from SARS-CoV-2 infection, respectively. …"
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6
Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture
منشور في 2018"…A series of photomagnetic coordination polymer core-shell heterostructures, based on the light-switchable RbaCob[Fe(CN)6]c·mH2O (RbCoFe-PBA) as core with the isostructural KjNik[Cr(CN)6]l·nH2O (KNiCr-PBA) as shell, are studied using temperature-dependent powder X-ray diffraction and SQUID magnetometry. …"
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7
Dispatchable capacity optimization strategy for battery swapping and charging station aggregators to participate in grid operations
منشور في 2023"…Also, the aggregator does not worsen the original power load while meeting the EV swapping demand and can decrease the daily load fluctuations by 0.65% and 12.89%, reduce the peak–valley difference by 5.81% and 7.80%, and increase the load rate by 3.67% and 4.08% in working and non-working day situations through providing the dynamic dispatchable capacity for the grid.…"
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8
Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
منشور في 2024"…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). Close to 90 % of all positive diagnoses were among MSM. …"
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9
Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
منشور في 2025"…The SSI incidence in LMICs was 8.0 % (95 % CI: 6.0 %–10.0 %) with moderate certainty, while the incidence in HICs was 5.0 % (95 % CI: 4.0 %–7.0 %) with low certainty. …"
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10
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
منشور في 2024"…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. …"
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …"
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12
Effects of financial turmoil on financial integration and risk premia in emerging markets
منشور في 2016"…Our sample consists of monthly data for 12 emerging stock markets over the period 1988M3-2015M3. We find that while the financial integration of emerging stock markets has registered short-term reversals episodes in countries that have been exposed to national or/and regional financial crises, it has decreased in most of the emerging countries of our sample since the global crisis. …"
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15
Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties
منشور في 2022"…It is found that the optimal ferroelectric and piezoelectric values were obtained at 1150 °C (P r = 27 µC/cm 2 , E c = 3.89 kV/mm and d 33 = 110 pC/N). According to these results, we suggest that 850 °C and 1150 °C can be considered as optimal calcination and sintering temperature in NBT-6BT ceramic, respectively.…"
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16
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
منشور في 2025"…ResultsThe course included 18 participants (10 female, 8 males; average age 40.18 ± 8.46 years) categorized as novice (n = 10, <3 years’ experience), intermediate (n = 5, 3-5 years), and expert (n = 3, >5 years). Video evaluations did not reveal significant differences due to short-term training. …"
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
منشور في 2023"…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …"
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18
Electrically conductive hybrid organic crystals as flexible optical waveguides
منشور في 2022"…The elements respond rapidly to temperature by curling or uncurling in about 0.2 s, which in one typical case corresponds to exceedingly fast deformation and recovery rates of 2187.5° and 1458.3° , respectively. In cyclic operation mode, their conductivity decreases less than 1% after 10,000 thermal cycles. …"
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19
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
منشور في 2024"…We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60·1% [95% UI 56·8–63·1] of DALYs were from CMNNs in 2022 compared with 35·8% [31·0–45·0] in 2050) and south Asia (31·7% [29·2–34·1] to 15·5% [13·7–17·5]). …"
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
منشور في 2024"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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