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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
منشور في 2024"…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact
منشور في 2020"…The results showed a decrease in the MSE of V<sub>mp</sub> by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I<sub>mp</sub> by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained?
منشور في 2025"…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 <sub>year9 </sub>mmol/L. …"
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
منشور في 2025"…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …"
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Flexural Response of Reinforced Concrete One-Way Slabs Embedded with Pet Bottles
منشور في 2023احصل على النص الكامل
doctoralThesis -
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Exploring the potential of applying Sustainable Retrofitting Policies & Regulations for existing low-rise small-scale Residential Buildings (Villas) in Dubai, UAE
منشور في 2020"…The highest energy savings were achieved from changing the AC set point 5.61%. While the lowest energy savings comes from adding external shadings with 0.87%. …"
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
منشور في 2010"…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …"
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Zirconium phytate-based proton conductors for high-temperature fuel cell applications
منشور في 2023احصل على النص الكامل
doctoralThesis -
14
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…Furthermore, OGD does not affect the half-life of ODD-luc protein following hypoxia, suggesting that OGD abrogates hypoxic HIF-1α induction by reducing HIF-1α synthesis rather than by enhancing its degradation. We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. …"
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. These findings were associated with higher level of oxidative stress (GP91 expression and malondialdehyde level) and elevated expression of key regulators of apoptosis (Bax and caspase-3) as well as reduced expression of mitochondrial respiratory chain complexes SDHB (II), UQCRC2 (III), and ATP5a (V) in the testicular tissue.…"
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Children safety risk factors in Khorasan Razavi province
منشور في 2015"…The study focused on rural roads in Khorasan Razavi province. Data came from police records and forensic medicine processed from 2010 to 2015. …"
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Characterizing the dynamics of climate and native desert plants in Qatar
منشور في 2024"…However, the probability of rainfall events over 80 mm was less than 5%, while low rainfall seasons (1–17 mm) were more likely (90–99% chance). …"
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A Machine Learning Approach on Chest X-Rays for Pediatric Pneumonia Detection
منشور في 2022احصل على النص الكامل
doctoralThesis -
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Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019
منشور في 2020"…</p><h3>Limitations</h3><p dir="ltr">There is no recognized optimal cut-off point to distinguish ‘high risk’ in pregnancy-related anxiety scales.…"