Gene-specific machine learning model to predict the pathogenicity of BRCA2 variants حسب Mohannad N. Khandakji (13885434)

"…<h3>Background</h3><p dir="ltr">Existing BRCA2-specific variant pathogenicity prediction algorithms focus on the prediction of the functional impact of a subtype of variants alone. …"

A comparative study of RSA based digital signature algorithms حسب Haraty, Ramzi A.

"…After factorization is found, the RSA problem could be solved by finding the private key using the extended Euclidean algorithm.…"
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Optimization of Interval Type-2 Fuzzy Logic System Using Grasshopper Optimization Algorithm حسب Saima Hassan (14918003)

"…The main objective of this paper is to apply GOA to estimate the optimal parameters of the Gaussian membership function in an IT2-FLS. The antecedent part parameters (Gaussian membership function parameters) are encoded as a population of artificial swarm of grasshoppers and optimized using its algorithm. …"

Rigorous Phase Equilibrium Calculation Methods for Strong Electrolyte Solutions: The Isothermal Flash حسب Ilias K. Nikolaidis (9217172)

"…In this way, an augmented function (Lagrange function) is formulated which serves as the basis for the equations that govern phase equilibrium. …"

Improved Dwarf Mongoose Optimization for Constrained Engineering Design Problems حسب Agushaka, Jeffrey O.

"…This paper proposes a modified version of the Dwarf Mongoose Optimization Algorithm (IDMO) for constrained engineering design problems. …"
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Design of an innovative and self-adaptive-smart algorithm to investigate the structural integrity of a rail track using Rayleigh waves emitted and sensed by a fully non-contact las... حسب Masurkar, Faeez

"…SASA is found to be able to suppress the unwanted wave packets from the overall signal leaving behind only the incident wave for a healthy spec imen, and the incident wave and its reflection from the defect for a damaged specimen. The functioning of the algorithm was successfully tested by carrying out extensive experiments on a real rail track in the presence of different types of surface and sub-surface defects on its head and web. …"
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Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19 حسب Hibah Shaath (5599658)

"…Further analyses revealed genes associated with the inflammatory response and chemotaxis of myeloid cells, phagocytes, and granulocytes, among the top activated functional categories in BAL from severe COVID-19-affected patients. …"

Optimizing clopidogrel dose response حسب Saab, Yolande B.

"…Purpose Response to clopidogrel varies widely with nonresponse rates ranging from 4% to 30%. A reduced function of the gene variant of the CYP2C19 has been associated with lower drug metabolite levels, and hence diminished platelet inhibition. …"
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Economic Production Lot-Sizing For An Unreliable Machine Under Imperfect Age-Based Maintenance Policy حسب El-Ferik, S

"…Numerical results are provided to illustrate both the use of the algorithm in the study of the optimal cost function and the latter's sensitivity to different changes in cost factors. …"
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Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia حسب Hanan Ehtewish (17149825)

"…We used a high-throughput proximity extension immunoassay to quantify 1090 proteins in 122 participants (22 with dementia, 64 with mild cognitive impairment (MCI), and 36 controls with normal cognitive function). Limma-based differential expression analysis reported the dysregulation of 61 proteins in the plasma of those with dementia compared with controls, and machine learning algorithms identified 17 stable diagnostic biomarkers that differentiated individuals with AUC = 0.98 ± 0.02. …"

Estimating Bridge Deterioration Age Using Artificial Neural Networks حسب AL HUSSEIN, ASEEL

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Detecting protein complexes in protein interaction networks using Mapper and Graph Convolution Networks حسب Daou, Leonardo

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Structural alignment. (c2006) حسب Kazma, Layal

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A lightweight adaptive compression scheme for energy-efficient mobile-to-mobile file sharing applications حسب Sharafeddine, Sanaa

"…However, the computational as well as memory access requirements of compression algorithms could consume more energy than simply transmitting data uncompressed. …"
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Isolating Physical Replacement of Identical IoT Devices Using Machine and Deep Learning Approaches حسب Mohammad, Areej Osama

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Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes حسب Radhakrishnan Vishnubalaji (3563306)

"…Differential expression and gene set enrichment analysis in TNBC revealed enrichment in the cycle and mitosis functional categories in FDPShigh, while ENO1high was associated with numerous functional categories, including cell cycle, glycolysis, and ATP metabolic processes. …"

Optimizing overheating, lighting, and heating energy performances in Canadian school for climate change adaptation: Sensitivity analysis and multi-objective optimization methodolog... حسب Mutasim Baba, Fuad

"…Ten building design variables are selected, which could generate approximately 300,000 solutions. The developed methodology reduced the numbers to 14,400 solutions and found seven Pareto solutions that comply with the three objectives and their constraints. …"
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StackDPPred: Multiclass prediction of defensin peptides using stacked ensemble learning with optimized features حسب Muhammad Arif (769250)

"…We believe, StackDPPred could serve as a valuable tool accelerating the screening of large-scale DPs and peptide-based drug discovery process.…"

Cohen syndrome and early-onset epileptic encephalopathy in male triplets: two disease-causing mutations in VPS13B and NAPB حسب Alice AbdelAleem (17753799)

"…Homozygosity mapping of ES data of this consanguineous family revealed multiple chromosomal regions of homozygosity stretches with the residing of VPS13B (chr8: 100830758G > A) and NAPB (Chr20: 23,375,774 A > C) variants within the largest homozygous blocks further supporting the disease-genes causal role. Interestingly, the functions of the two proteins; VPS13B, a transmembrane protein involved in intracellular protein transport, and SNAP-beta involved in neurotransmitters release at the neuronal synaptic complexes, have been associated with Golgi-mediated vesicular trafficking. …"

Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics حسب Abbas Khan (5141000)

"…Hence, the current study focuses on the screening of clinically reported substitutions in the <i>RAF1</i> and <i>RAP1A</i> genes using predictive algorithms integrated with all‐atoms simulation, essential dynamics, and binding free energy methods. …"