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ROC curve and AUC value of all models.
منشور في 2024"…As for Specificity (82.94%) and ROC-AUC (82.13%), the Multilayer Perceptron with SGD optimizer obtained the highest scores. …"
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<b>Supporting data for manuscript</b> "<b>Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins</b>"
منشور في 2025"…<p dir="ltr">The CSV file 'Eyreetal_DrainingVein_SourceData' contains the averaged time series traces and extracted metrics from individual experiments used across Figures 1-5 in the manuscript "Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins". The following acronyms included in the CSV file are defined as follows: Hbt is total hemoglobin, Art is artery region, DV is draining vein region, WV is whisker vein region, SEM is standard error mean, TS is time series, max peak is maximum peak, min peak is minima, AUC is area under the curve, WT is wild-type, AD is Alzheimer's disease, ATH is atherosclerosis and MIX is mixed AD/atherosclerosis. …"
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AUC statistics as calculated from simulated time series. Each statistical metric was calculated within sliding windows, throughout the pre-critical interval. We considered five-, fifteen-, and thirty-day sliding windows. Given that the temperature of the system increased to 12°C on day sixty, we also considered three pre-critical intervals: Days 1 to 60, Days 20 to 60, and Days 30 to 60. To evaluate trends in these metrics, we calculated Kendall’s rank correlation coefficient during the pre-critical interval, and compared control (constant temperature, non-epidemic) and warming (warming treatment, epidemic emergence) coefficients across simulations and experimental populations by calculating the area under the curve (AUC) statistic. Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre
منشور في 2025"…To evaluate trends in these metrics, we calculated Kendall’s rank correlation coefficient during the pre-critical interval, and compared control (constant temperature, non-epidemic) and warming (warming treatment, epidemic emergence) coefficients across simulations and experimental populations by calculating the area under the curve (AUC) statistic. Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre</p>…"
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Statistical analysis of the AUC measurement.
منشور في 2025"…<p>Analysis indicated that INSv application significantly changed spontaneous calcium activity (IAsp <i>p</i>-value: 0.1290, INSv <i>p</i>-value: 0.0002). The mean AUC decreased in both samples.…"
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Flow diagram of participants selection.
منشور في 2025"…Each10 units increase in BRI, ASM/ BMI decreased by 29% (β = −0.29,95% CI: −0.31, −0.28, <i><i>p</i></i> value < 0.0001). …"
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Minimal data set.
منشور في 2025"…Each10 units increase in BRI, ASM/ BMI decreased by 29% (β = −0.29,95% CI: −0.31, −0.28, <i><i>p</i></i> value < 0.0001). …"
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Weighted comparison of baseline characteristics.
منشور في 2025"…Each10 units increase in BRI, ASM/ BMI decreased by 29% (β = −0.29,95% CI: −0.31, −0.28, <i><i>p</i></i> value < 0.0001). …"