Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization حسب Adrián Martín‐Segura (18615133)

"…Furthermore, in vivo inhibition of Cyp46A1, an enzyme involved in brain cholesterol loss with age, improved insulin signaling. …"

Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy حسب Khoury, Reine

"…The brain’s cognitive skills gradually decline with aging. …"
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Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism حسب Ramya Potabattula (4401160)

"…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …"

Lipid profile in Parkinson's disease: The potential role of brain-derived neurotrophic factor حسب Mahmoud A. Alomari (14780446)

"…Brain-derived neurotrophic factor (BDNF) is essential for neurocognitive function. …"

The outcome of severe traumatic brain injury in children in Qatar: Six-year study حسب Azhar Khattab (19774476)

"…<p dir="ltr">The aim of this study was to determine the incidence pattern of the burden severe traumatic brain injuries (TBIs) among young children in Qatar and to suggest practical prevention policies that can be implemented in Qatar. …"

Breaking the barriers towards large-scale microalgae-based bio-hydrogen production حسب Isra Koko (22631396)

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…HIC showed decreased FA and increased MD in multiple brain sites as compared to both CHNM and HUC. …"
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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury حسب Sebnem Garip Ustaoglu (18460611)

"…<div><p>Traumatic brain injury (TBI) is the main cause of disability and mortality in individuals under the age of 45 years. …"

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial حسب Hourani, R.

"…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …"
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Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF حسب Jabr, Vanessa

"…In this study, we demonstrated that a short-term voluntary exercise paradigm is sufficient to upregulate autophagy in different brain regions in an age-dependent manner. This increase in autophagy was correlated with enhanced spatial learning and memory formation particularly in mature adult mice (10-week-old). …"
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Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls حسب Daniel Erskine (3471959)

"…Therefore, we sought to determine whether older individuals with mitochondrial diseases were at increased risk of developing age-associated neurodegenerative pathologies using post-mortem brain samples collected prospectively at Newcastle Brain Tissue Resource (NBTR).…"

Programming Effects of Short Prenatal Exposure to Dexamethasone in Sheep حسب Abouantoun, Tamara

"…The aims of the present study were to see whether prenatal dexamethasone administered intravenously to the ewe between 26 to 28 days of gestation (1) resulted in high blood pressure in male and female offspring and whether hypertension in males was modulated by testosterone status, and (2) altered gene expression for angiotensinogen and angiotensin type 1 (AT1) receptors in the brain in late gestation and in the adult. Basal mean arterial pressure (MAP) at 2 years of age was significantly higher in wethers exposed to prenatal dexamethasone (group D; 106 5 mm Hg, n9) compared with the control group (group S; 91 3 mm Hg, n8; P0.01). …"
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging حسب Dimassi, Hani

"…We undertook this study to investigate the relationship between white-matter abnormalities (seen on brain magnetic resonance imaging [MRI]) and muscle tone and muscle stretch reflexes on clinical examination. …"
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''Effectiveness of Non-invasive Positive Pressure Ventilation in ELBW Infants: A Comparison of Successful and Failed Outcomes'' حسب Ratheesh Paramban (17046388)

"…More babies in the NIPPV-success group were on room air at 28 days of age (30.2% vs 4.2%, p=0.016) and at 36 weeks postmenstrual age (81.4% vs 58.3%). …"

Building A Passive Thermal Management System Using Phase Change Material Embedded In Porous Media حسب Azzam, Mohammed H. A.

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Population‐Based Norms for the Montreal Cognitive Assessment in Arab Adults حسب Iman Amro (13996378)

"…<h3>Objective</h3><p dir="ltr">The Montreal Cognitive Assessment (MoCA) is a brief screening instrument for detecting mild cognitive dysfunction, a precursor to many cognitive disorders, such as dementia, which have increased in prevalence globally. Qatar, a small high‐income country, has the largest projected increase in dementia of any country in the Middle East. …"

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

"…In view of the increased risk of developing AD in T21 individuals, we additionally investigated the T21-associated sites in published blood DNA methylation data from the AgeCoDe cohort (German study on Ageing, Cognition, and Dementia). …"

Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments حسب Fares Almomani (12585685)

"…Further improvement was achieved via alkalinity treatment with 1.0 g of NaHCO₃/gVS leading to decrease in lignin, cellulose, and hemicellulose contents of feedstock by 3.5%, 10.5% and 15.9%, respectively, converting them to soluble fractions and improving the CMP by 11.2–29.7% based on substrate quality. …"

Impact of seafood and fruit consumption on bone mineral density حسب Zalloua, Pierre A.

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Diagnostic, Prognostic, and Mechanistic Biomarkers of Diabetes Mellitus-Associated Cognitive Decline حسب Hanan Ehtewish (17149825)

"…This review aims to provide a comprehensive background of the potential risk factors, the identified biomarkers of diabetes-related cognitive decrements, and the underlying processes of diabetes-associated cognitive dysfunction. Aging, poor glycemic control, hypoglycemia and hyperglycemic episodes, depression, and vascular complications are associated with increased risk of dementia. …"