α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain حسب Eid, Fady

"…Moreover, aKG exhibited antidepressant effects in susceptible female mice by modulating BDNF levels. In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Brain and plasma riluzole pharmacokinetics حسب Milane, Aline

"…In a previous study, we showed that riluzole is transported out of the brain by the P-glycoprotein at the bloodbrain barrier level. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains حسب Riachi, Naji J.

"…Decreased striatal dopamine levels in these latter rat strains were associated with increased dopamine turnover. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Exercise-induced a-ketoglutarate enhances spatial learning by modulating hippocampal levels of BDNF in a sex-specific manner حسب Al Ahmad, Perla

"…The exercise factors increase hippocampal levels of brain-derived neurotrophic factor (BDNF) which mediates the benefits of exercise on cognition. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

ABCB1 (P-glycoprotein) and blood-brain barrier حسب Milane, Aline

"…ABCB1 is involved in drug pharmacokinetics: at the blood-brain barrier level, due to its luminal localisation, ABCB1 limits drug transport and plays an important role in central detoxification. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Breaking the barriers towards large-scale microalgae-based bio-hydrogen production حسب Isra Koko (22631396)

Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) حسب Khoury, Oula

احصل على النص الكامل
احصل على النص الكامل

Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy حسب Yahya, Fares

احصل على النص الكامل

Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study حسب Stefania, Mondello

"…BackgroundGlycans play essential functional roles in the nervous system and their pathobiological relevance has become increasingly recognized in numerous brain disorders, but not fully explored in traumatic brain injury (TBI). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury حسب Judith, Nwaiwu

"…Results showed that while WD significantly increased fat percentage and elevated plasma cholesterol, there was no change in blood glucose level or body weight, indicating an early stage of MetS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) حسب Jabre, Mazen Gerges

"…The mean levodopa dose was reduced by 90% (p < 0.01), while the mean dopamine agonist dose was increased by 15% from preoperative level. Reported adverse events were mild and transient. …"
احصل على النص الكامل
احصل على النص الكامل

Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy حسب Khoury, Reine

"…The brain’s cognitive skills gradually decline with aging. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Expression of 3-Methylcrotonyl-CoA Carboxylase in Brain Tumors and Capability to Catabolize Leucine by Human Neural Cancer Cells حسب Eduard Gondáš (18877708)

"…It is readily imported from the bloodstream into the brain parenchyma. Therefore, it could serve as a putative substrate that is complementing glucose for sustaining the metabolic needs of brain tumor cells. …"

Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization حسب Adrián Martín‐Segura (18615133)

"…The application of a cholesterol inclusion complex, which donates cholesterol to the membrane and increases membrane cholesterol levels, rescued the insulin signaling deficit and insulin‐LTD. …"

Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain حسب Mohamed H. M. Ali (5768066)

"…Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …"

Combinatory effect of diet and exercise on brain derived neurotrophic factor expression, cognitive function and behavioral phenotypes of psychiatric disorders. (c2017) حسب Abou Haidar, Edwina T.

"…Its involvement in the learning processes and memory formation has also been well established. BDNF levels are dramatically decreased in the adult brain in response to stress and are elevated by increased exercise. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effectiveness of Brain Gym® Exercises on Improving Students’ Performance in classes of middle school boys in private schools in Dubai, UAE(Ethnographic Study Conducted at the A... حسب AL HERBAWI, DUA’A

"…The research concluded that Brain Gym® exercises were indeed effective in improving the behavior and attitudes of the students and in making them more focused in what they doing in class, however, more researches should be done to prove the effectiveness of these exercises on increasing the academic level in terms of educational attainment.…"
احصل على النص الكامل

Lactic acid mediates the effects of physical exercise on learning and memory through SIRT1-dependent activation of hippocampal BDNF. (c2018) حسب Hayek, Lauretta El

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF حسب Jabr, Vanessa

"…Indeed, we showed that short-term voluntary wheel running increases the protein expression levels of the autophagy marker, protein light chain 3 (LC3B), in the hippocampus of 10-week-old mice. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Investigation of Biochemical Alterations in Ischemic Stroke Using Fourier Transform Infrared Imaging Spectroscopy—A Preliminary Study حسب Fazle Rakib (5768069)

"…<p dir="ltr">Objective: Brain damage, long-term disability and death are the dreadful consequences of ischemic stroke. …"