Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines حسب Ismail, Jana

"…The results suggest the potential benefit of sequential, rather than simultaneous, administration of CBD and chemotherapy to enhance therapy and overcome resistance. These findings, while demonstrating the potential benefit of CBD in treating ovarian cancer, call for additional caution when combining it with chemotherapeutic agents, specifically cisplatin and paclitaxel, as the effect is shown to be cell line and drug specific. …"
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…These results suggest a physiological role of DNAJB3 in mitigating metabolic stress and improving glucose homeostasis and could therefore represent a novel therapeutic target for type 2 diabetes.…"

Empiric antibiotic therapy of community-acquired Pneumonia at the American University of Beirut Medical Center. (c2001) حسب Cherfan, Antoine

"…The emergence of resistance among Streptococcus pneumoniae strains have led to the development of several guidelines for the treatment of community-acquired Pneumonia (CAP). …"
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

"…This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …"

Prophylactic and therapeutic antibiotic patterns of lebanese dentists for the management of dentoalveolar abscesses حسب Mokhbat, J.

"…The main prescribed antibiotic was amoxicillin.This study showed that dentists often did not follow the current prophylactic and therapeutic antibiotic prescription guidelines.Antibiotics prescriptions in dentistry will be more pertinent, leading to a decrease in inadequacy of prescriptions, microbial resistance, and the development of multiresistant germs against antibiotics…"
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Dicarbonyl stress, protein glycation and the unfolded protein response حسب Naila Rabbani (291722)

"…An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…<div><p>Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account for the high mortality rate. …"

The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review حسب Mahmoud Yousef (9900837)

"…Noteworthy prebiotics employed in these studies included chestnut tannin, galactooligosaccharides, fructooligosaccharides, xylooligosaccharide, and resistant dextrin. The majority of the investigated biotics exhibited positive effects on COVID-19 patients, manifesting in symptom alleviation, inflammation reduction, and notable decreases in mortality rates. …"

Effect of water extract of Althaea officinalis flowers on inflammation, gastric ulcer, bacterial activity, platelet aggragation, glycemia, and lipidemia. (c2006) حسب Hage-Sleiman, Rouba

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Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation حسب Kodappully S. Siveen (4246150)

"…Challenging lung airway epithelial cells (AECs) with LBCs decreased (by more than 50%) transepithelial resistance (TER) denoting barrier function alteration. …"

Candida albicans identification and microsatellite DNA genotyping of Lebanese clinical isolates. (c2007) حسب Barada, Ghyda Ali

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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…Normal cells, on the other hand, were resistant to HuArgI (Co)-PEG5000-induced arginine deprivation. …"
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…Glioblastoma multiforme (GBM) is a highly aggressive glioma arising in the central nervous system accounting for more than 70% of all brain tumors. Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. …"
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…In conclusion, our findings demonstrated that Ruxolitinib and CHIR-99021 could be promising therapies in targeting neuroblastoma CSCs, and that combining these two drugs may have added therapeutic effects in treating this malignant tumor. …"
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon حسب Mokhbat, Jacques M.

"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines حسب Soukarieh, Rania

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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

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Immunoprofile of childhood diabetes حسب Meritxell Espino-Guarch (15430868)

"…Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies حسب Sabah Nisar (12561961)