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Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19
منشور في 2021"…<div><p>Hyperactivation of the immune system through obesity and diabetes may enhance infection severity complicated by Acute Respiratory Distress Syndrome (ARDS). …"
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Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis
منشور في 2022"…</p> <h2>Results</h2> <p>The data demonstrated a significant increase in microbiome diversity denoted by higher relative abundances of phylum Proteobacteria (p = 0.031), Fusobacteria (p = 0.044) and genus Streptococcus (p ≤ 0.001) in the infected group relative to the control. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Epidemiological, Molecular, and Clinical Features of Norovirus Infections among Pediatric Patients in Qatar
منشور في 2019"…NoV infections occurred throughout the year, with a noticeable increase in summer (36.6%) and drop in winter (25.4%). …"
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DNA methylation predicts the outcome of COVID-19 patients with acute respiratory distress syndrome
منشور في 2022"…<h3>Background</h3><p dir="ltr">COVID-19 infections could be complicated by acute respiratory distress syndrome (ARDS), increasing mortality risk. …"
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SARS-CoV-2 Infection and Smoking: What is the association? A brief review
منشور في 2021"…Smoking has been shown to enhance the expression of the angiotensin-converting enzyme-2 (ACE-2) and transmembrane serine protease 2 (TMPRSS2) key entry genes utilized by SARS-CoV-2 to infect cells and induce a ‘cytokine storm’, which further increases the severity of COVID-19 clinical course. …"
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The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues
منشور في 2022"…The emergence of these VOCs (Alpha, Beta, Gamma, and Delta) variants was responsible for new waves of infections across the entire world [3]. The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …"
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Evaluation of the risk of acute kidney injury with the use of piperacillin/tazobactam among adult critically ill patients
منشور في 2020"…<h3>Purpose</h3><p dir="ltr">Piperacillin/tazobactam (PT), when combined with vancomycin, is associated with an increased risk of acute kidney injury (AKI). It is not known whether PT alone is associated with a higher incidence of AKI compared to other β-lactams among critically ill patients. …"
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Ischemic stroke in the setting of supratherapeutic International Normalized Ratio following coronavirus disease 2019 infection: a case report
منشور في 2023"…<h3>Background</h3> <p>SARS-CoV-19 infection is associated with an increased risk of thrombotic events. …"
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Ischemic stroke in the setting of supratherapeutic International Normalized Ratio following coronavirus disease 2019 infection: a case report
منشور في 2023"…<h3>Background</h3><p dir="ltr">SARS-CoV-19 infection is associated with an increased risk of thrombotic events. …"
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SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study
منشور في 2023"…Risk of infection varied minimally by age and sex but increased significantly with coexisting conditions. …"
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…Background: Upper respiratory infections (URIs) are the leading cause of acute disease incidence worldwide and contribute to a substantial health-care burden. …"
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Impact of COVID‑19 pandemic restrictions and subsequent relaxation on the prevalence of respiratory virus hospitalizations in children
منشور في 2024"…We compared the number and severity of viral acute lower respiratory tract infection (ALRTI) hospitalizations and determined changes in causative respiratory pathogens before, during, and after the pandemic among young children in Qatar.…"
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SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
منشور في 2024"…Here, we investigated ADCC activity in convalescent sera from infected patients with wild‐type (WT) severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) or omicron variant compared with three coronavirus disease 2019 (COVID‐19) vaccine platforms and postvaccination breakthrough infection (BTI). …"
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Prophylactic and therapeutic antibiotic patterns of lebanese dentists for the management of dentoalveolar abscesses
منشور في 2016"…The use of antibiotics for the management of dentoalveolar infections should be considered only in the presence of an increased risk of a systemic involvement or to prevent metastatic infections. …"
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
منشور في 2022"…We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B.</p><h3>Findings</h3><p dir="ltr">In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. …"