DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…The ability of DNAJB3 to mitigate ER stress and oxidative stress was also investigated and our data show a significant improvement of both forms of stress. …"

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies حسب Sabah Nisar (12561961)

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

Dicarbonyl stress, protein glycation and the unfolded protein response حسب Naila Rabbani (291722)

"…An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …"

Thermal, electrical, and mechanical properties of highly filled HDPE/graphite nanoplatelets composites حسب A.U. Chaudhry (17075308)

"…On the other hand, the degree of crystallinity and melting temperature decreased with GNPs content. The incorporation of GNPs greatly decreased the electrical resistivity by 10 orders of magnitude and 400% increase in thermal conductivity for filled HDPE was also observed. …"

Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites حسب Mehdi Soleymani (3347741)

"…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …"

Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines حسب Ismail, Jana

"…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …"
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"

Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inf... حسب Naila Rabbani (291722)

"…These findings suggest tRES-HESP counters MG accumulation and protein glycation, decreasing activation of the unfolded protein response and expression of TXNIP and TNFα, producing reversal of insulin resistance. tRES-HESP is suitable for further evaluation for treatment of insulin resistance and related disorders.…"

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature حسب Maha Sellami (4351159)

"…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. …"

Soil Characterization Utilizing GPR Technique حسب Al Kej, Fateh Tamam

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Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue حسب Ali Tiss (437068)

"…<p dir="ltr">Obesity is characterized by a chronic low-grade inflammation and altered stress responses in key metabolic tissues. Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …"

Online Monitoring of Outdoor Non-Ceramic Insulators حسب Shurrab, Ibrahim Yehia

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Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover حسب Naila Rabbani (291722)

"…Further research to decrease protein glycation in plants may lead to improved plant growth and assist the breeding of plant varieties resistant to environmental stress and senescence—including plants of commercial ornamental and crop cultivation value.…"

Optoelectronic properties of highly porous silver oxide thin film حسب Ahmad Al-Sarraj (17151007)

"…The Ag₂O phase of silver oxide appears after 300 s of oxidation under the same conditions, while the optical transparency of the thin film decreases as plasma etching time increases. The sheet resistance of the final film is influenced by the oxidation time and the plasma application periodicity.…"

Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO₂- saturated saline solution حسب Rem Jalab (11715205)

Phenotypic and cell wall proteomic characterization of a DDR48 mutant candida albicans strain حسب El Khoury, Pamela

"…A DDR48 haploinsufficient mutant strain was previously found necessary for proper oxidative stress response and drug resistance. In this study, we aimed to further elucidate the role of Ddr48 by performing additional phenotypic characterization assays. …"
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Phenotypic and proteomic characterization of Dbr48, a candida albicans cell wall protein. (c2018) حسب Salameh, Carell C.

"…Our results showed that the heterozygous mutant strain exhibited a 10% decrease in adhesion mirrored by a 20% decrease in biofilm formation, and a slight sensitivity to oxidative stress agents and SDS. …"
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