Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies حسب Sabah Nisar (12561961)

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…<p>Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue حسب Ali Tiss (437068)

"…<p dir="ltr">Obesity is characterized by a chronic low-grade inflammation and altered stress responses in key metabolic tissues. Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …"

Welding of Semiconductor Nanowires by Coupling Laser-Induced Peening and Localized Heating حسب Kelly M. Rickey (19568770)

"…The morphology results show that laser peening can decrease porosity and bring nanowires into contact and pulsed laser heating fuses those contacts. …"

Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review حسب Muhammad Asim (2235472)

"…This study presents the evaluation of performance parameters and the manufacturing aspects of microchannel heat exchangers. This study also examines how microchannel heat exchangers are affected by several parameters, including the type of working fluid used, Brownian motion, geometry of the channel, Reynolds number, Nusselt number, Knudsen number, wall resistance of the channel, the effect of gravity, and inlet and outlet arrangement for fluid. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

Heat transfer measurements of Polyalpha-Olefin- boron nitride nanofluids for thermal management and lubrication applications حسب Ahmad K. Sleiti (14778229)

"…Two competing phenomena affect the heat transfer performance: the increase/decrease in resistance to thermal diffusion sublayer when thermal conductivity increases and viscosity decreases, respectively. …"

Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines حسب Ismail, Jana

"…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …"
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Thermally Conductive Polyethylene/Expanded Graphite Composites as Heat Transfer Surface: Mechanical, Thermo-Physical and Surface Behavior حسب Patrik Sobolčiak (4401364)

"…<p dir="ltr">Composites of high-density polyethylene (HDPE) and expanded graphite (EG) are prepared for heat exchangers in multi-effect distillation (MED) desalination. …"

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"

Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inf... حسب Naila Rabbani (291722)

"…These findings suggest tRES-HESP counters MG accumulation and protein glycation, decreasing activation of the unfolded protein response and expression of TXNIP and TNFα, producing reversal of insulin resistance. tRES-HESP is suitable for further evaluation for treatment of insulin resistance and related disorders.…"

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature حسب Maha Sellami (4351159)

"…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. …"

Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes حسب Mohammad Amir Khan (23770803)

"…These results point to a scalable approach for developing lightweight corrosion resistant thermal management composites that can be used in the design of energy efficient wall panels and heat-dissipative building materials.…"

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Despite the recent advances, many children continue to suffer from refractory and relapsed diseases, and they often develop metastatic tumors resistant to standard treatments. Amplification of MYC-N proto-oncogene is highly associated with clinically aggressive disease, recurrence and treatment failure. …"
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Isolation and study of Lipase activity of an olive oil degrading Thermoactionomyces SP. (c2002) حسب Al Khudary, Rami

"…This lipolytic enzyme showed resistance to boiling and to a wide range of metallic 10ns and inhibitors. …"
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Characterization of Dse1 a candida albicans cells wall protein. (c2009) حسب Daher, Jalil Y.

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Reactions, Adsorption and Diffusion in FCC Catalysts حسب Mahaly, Wafa

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