A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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Mechanical Efficiency at Different Exercise Intensities Among Adolescent Boys With Different Body Fat Levels حسب Georges Jabbour (754884)

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"

Exploring of the gender variations in 4Cs skills among primary students حسب Azza Saad (18255742)

"…The purpose of this study was to explore gender differences in 4Cs skills between males and females among the primary students after the execution of an informal program. …"

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"

Comparative Analysis of Engagement and Academic Self‐Concept among Nursing Students: Differences in Study Modalities حسب Esraa Elsayed Rushdan (20884220)

"…</p><h3>Results</h3><p dir="ltr">Significant differences were observed in the USEI scores among the study modalities: online (mean = 45.7, SD = 5.6), hybrid (mean = 48.8, SD = 6.1), and in‐person (mean = 50.4, SD = 6.2), with in‐person students displaying the highest levels of engagement (<i>F</i>= 10.663, <i>P</i>< 0.001). …"

Differences in Player Position Running Velocity at Lactate Thresholds Among Male Professional German Soccer Players حسب René Schwesig (6786632)

"…<p dir="ltr">This study investigated the differences in running velocities at specific lactate thresholds among male German soccer players. …"

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…RNA-sequencing analysis further validated the findings by showing a significant increase in genes associated with lipid metabolism, bile acid secretion, and suggested the activation of hepatic stellate cells and hepatic fibrosis in MH lacking FOXA2. …"

Exploring differences in work values among multigenerational workforce: Leadership approaches in selected higher educational institutions in the UAE حسب AL MARZOOQI, LOLOWA

"…According to the present thesis, there are significant differences in work values between the three generations in UAE, which in turn differ from the values of employees from the Western countries. …"
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Playing Level and Position Differences in Body Characteristics and Physical Fitness Performance Among Male Team Handball Players حسب Souhail Hermassi (6919487)

Seroprevalence of West Nile Virus among Healthy Blood Donors from Different National Populations Residing in Qatar حسب Soha R., Dargham

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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …"

Benthic development on large-scale engineered reefs: a comparison of communities among breakwaters of different age and natural reefs حسب Burt, John

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Gender-based differences in the prevalence and types of adverse childhood experiences and their associations with psychological distress and perceived lack of safety among adolesce... حسب Hina Akram (14778205)

"…We explored gender differences in prevalence and associations of ACEs with psychological distress and feeling unsafe among Qatari adolescents using a 2017 national cross-sectional survey of 836 students (412 boys and 424 girls) from grades 8 to 12. …"

Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry حسب Isbaih, Sara Samir

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Gender differences at work حسب Ismail, Hussein N.

"…The findings show that women’s expectations at work were met to a larger extent than men’s. There was a significant difference in at least two HR practices including ‘recognition at work’ and ‘supporting managers/supervisors’. …"
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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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