-
1
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
-
2
-
3
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
-
4
-
5
-
6
-
7
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
-
8
Designing a Flexible and Reconfigurable Manufacturing System Considering a Circular Shaped Layout
منشور في 2018احصل على النص الكامل
doctoralThesis -
9
Engineering PLA-MXene nanocomposite with balanced mechanical properties for enhanced shape memory effect
منشور في 2024"…The PLA/Mx composite exhibited a significantly improved shape memory effect than the PLA alone. …"
-
10
-
11
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
-
12
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
-
13
-
14
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
15
Role of Active Morphing in the Aerodynamic Performance of Flapping Wings in Formation Flight
منشور في 2021"…This arrangement enables an increase in the overall efficiency of the group because the wake vortices shed by each of the birds provide additional lift and thrust to every member. …"
احصل على النص الكامل
article -
16
-
17
Double diffusive mixed convection and entropy generation analysis of NEPCM-water mixture in a π-shaped cavity
منشور في 2025"…Results demonstrate that Reynolds and Richardson numbers significantly enhance heat and mass transfer (up to 204 % increase in Nusselt number), while magnetic fields substantially suppress convective transport (60.5 % reduction in Nusselt number). …"
-
18
-
19
Design, Implementation, and Performance Analysis of Actively
منشور في 2023احصل على النص الكامل
doctoralThesis -
20
FEA Investigation of Elastic Buckling for Functionally Graded Material (FGM) Thin Plates with Different Hole Shapes under Uniaxial Loading
منشور في 2022"…Moreover, the lower the power law index, the higher the critical buckling load. The diamond shape opening shows the best performance in terms of the critical buckling load, and the effect of the plate thickness has a more significant influence on the critical buckling load of the FGM plate compared to the size of the opening.…"
احصل على النص الكامل
article