Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…In cell lines with robust SLFN11 promoter methylation such as MDA-MB-231, no SLFN11 expression could be induced by any approach.</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …"

Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study حسب Martins, Ana M.

احصل على النص الكامل

Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation حسب Salman, Zeina

"…While prior studies demonstrated the anti-inflammatory role of miR-27a-5p in FliC-induced inflammation, the roles of miR-222-5p and miR-21-3p remain unclear. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

"…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS حسب Myint Myint Aye (6404327)

"…The M value was significantly less in PCOS compared to controls for both saline (p < 0.01) and lipid (p < 0.05). …"

Board changes and CEO turnover حسب Dah, Mustafa A.

"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Therapeutic Impact of P-PENT, P-HEX and 5CLSS (IV) Platinum (IV) complexes on Acute Myeloid Leukemia in vitro and in vivo حسب Bou Chacra, Joelle

"…All three complexes caused significant cytotoxicity with IC50 values of 0.12, 0.070, and 0.12 μM for 5CLSS(IV), PPENT, and P-HEX, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Vocal Changes in Patients With Polycystic Ovary Syndrome حسب Hannoun, Antoine

"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Earthquake-induced landslide hazard mapping حسب Abou-Jaoude, Grace

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Characterization of exercise-induced hemolysis in endurance horses حسب Patrycja D. Pakula (19438024)

"…<p dir="ltr">Exercise-induced hemolysis occurs as the result of intense physical exercise and is caused by metabolic and mechanical factors including repeated muscle contractions leading to capillary vessels compression, vasoconstriction of internal organs and foot strike among others. …"

LASER INDUCED BREAKDOWN SPECTROSCOPY OF GEOLOGICAL SAMPLES حسب Gondal, M. A.

احصل على النص الكامل

Active laminar mixing induced by surface disturbance حسب Akle, Barbar

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The impact of different acidic conditions and food substrates on Listeria monocytogenes biofilms development and removal using nanoencapsulated carvacrol حسب Jina, Yammine

"…However, at pH 5.5 and 6.5, increased biofilm levels were observed in both the culture media and food substrates, with the WT strain showing significantly higher biofilm formation (3.04–6.05 log CFU cm−2) than the mutant strains (2.30–5.48 log CFU cm−2). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study حسب Mostafa Najim (14150400)

"…Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …"

Local arterial vasoconstriction induced by octreotide in patients with cirrhosis حسب Chatila, Rajaa

"…Saline infusion did not alter FBF, but octreotide infusion resulted in a 34% +/- 7.7 (P <.005) reduction in FBF in the infused arm. FBF in the control arm was unchanged despite a significant decrease in systemic glucagon levels. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A review of movement disorders in chemotherapy-induced neurotoxicity حسب Allison B. Wang (14153307)