Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …"

In Vitro Cell Work of Two Types of Targeted Nanoparticles with Ultrasound Triggering حسب Abuwatfa, Waad Hussein

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Knowledge, attitude, and practice of physicians regarding pain management in patients with Sickle cell disease حسب Abdellatif Ismail (14182309)

"…Pain from vaso-occlusive crises (VOCs) is the most common symptom experienced by patients with SCD; thus, pain management constitutes a significant role in this patient population. We hypothesized that physicians with less favorable attitudes toward SCD patients are less likely to follow pain management guidelines. …"

Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications حسب Edwin, Reeves Nayagam

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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines حسب Ismail, Jana

"…Thus, according to Drug Reduction Index (DRI), a combination of 6-fold less concentration of cisplatin with 1.3-fold less concentration of CBD yields a 95% cell growth inhibition. …"
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Single-cell protein production from purple non-sulphur bacteria-based wastewater treatment حسب Ojima Z. Wada (14155734)

"…<p>Large-scale production of single-cell protein (SCP) has the potential not only to solve some of the food insecurity and water scarcity crises that plague a significant portion of our world today but also holds the promise to reduce the cost associated with the treatment of industrial and agricultural wastewater. …"

Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells حسب Abi-Habib, Ralph J.

"…In addition, DTU2mGMCSF, a modified form of DT390mGMCSF with enhanced tumor cell specificity, was not hepatotoxic and was significantly less toxic to KC in vivo and in vitro. …"
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Evaluation of cell disruption methods for protein and coenzyme Q10 quantification in purple non-sulfur bacteria حسب Ojima Z. Wada (14155734)

"…Overall, PNSB required more intensive protein extraction techniques than were reported to be effective on other single-cell organisms. NaOH was the preferred chemical for chemical-aided mechanical/physical extraction as EDTA was observed to interfere with the Lowry protein kit, resulting in significantly lower concentrations. …"

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …"
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The anti-neoplastic activity of novel platinum II and IV complexes against A549 lung cancer cells حسب Al Sayegh, Rouba

"…While AK1 exhibited faster uptake and greater cytotoxicity, AK2 was by far less toxic to normal mesenchymal stem cells. Further in vivo studies are needed to confirm the efficacy and safety of AK1 and AK2.…"
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Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients حسب Sara Al-Khawaga (4792761)

"…The use of poorly characterized MSC products remains one of the most significant drawbacks of MSC-based therapy, which could theoretically promote the risk for thromboembolism. …"

A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction حسب Gillian Douglas (7759118)

"…However, Jcad^−/−ApoE^−/− mice developed significantly less atherosclerosis in the aortic root and the inner curvature of the aortic arch. …"

Absence of cardiac siderosis by MRI T2* despite transfusion burden, hepatic and serum iron overload in Lebanese patients with sickle cell disease حسب Inati, Adlette

"…TR was a much better predictor of iron burden (LIC, ferritin, NTBI) than TLT. In fact, TR less than 10 Units/yr did not produce significant iron overload reflecting spontaneous losses as high as 0.11 mg/kg/d. …"
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Urine as a Main Effector in Urological Tissue Engineering—A Double-Edged Sword حسب Tariq O. Abbas (11247771)

"…Thus, neo-organ construction through an alternative cell source might be useful. Significant advancements in the isolation and utilization of urine-derived stem cells have provided opportunities for this less invasive, limitless, and versatile source of cells to be employed in urologic tissue-engineered replacement. …"

Beta-Tocotrienol Exhibits More Cytotoxic Effects than Gamma-Tocotrienol on Breast Cancer Cells by Promoting Apoptosis via a P53-Independent PI3-Kinase Dependent Pathway حسب Idriss, Maya

"…Beta-tocotrienol exhibited a significantly more potent anti-proliferative effect than gamma-tocotrienol on both cell lines regardless of their hormonal receptor status. …"
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Minor Intron Splicing from Basic Science to Disease حسب Ettaib El Marabti (23276158)

Beyond genetics: Exploring the role of epigenetic alterations in breast cancer حسب Kirti S. Prabhu (4246144)

"…Its rising incidence is attributed to factors such as delayed diagnosis, the complexity of its subtypes, and increasing drug resistance, all contributing to less-than-ideal patient outcomes. Central to the progression of breast cancer are epigenetic aberrations, which significantly contribute to drug resistance and the emergence of cancer stem cell traits. …"

Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate حسب Alaa Elsafi (22282354)

"…For the same coatings, a significant light transmittance loss was measured in Doha (Qatar) compared to Uyaynah (Saudi Arabia). …"

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…"