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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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Editorial: Special Issue - Economics in Digital Construction
منشور في 2024"…These advancements promise substantial economic benefits, ranging from increased productivity to enhanced decision-making capabilities, which, in turn, can spur significant growth in the broader economy. …"
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Economic policy uncertainty: Global energy security with diversification
منشور في 2024"…This study also demonstrates that labor capital shifts have a significant effect on ED. The quantitative results reveal the importance of clear and precise economic policies for increasing investment in carbon-free energy security.…"
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
منشور في 2015"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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Techno-Economic Analysis of Autotrophic Microalgae for Biofuel Production in India
منشور في 2013"…Modern society relies on non-renewable sources of energy which is the dominant source of energy, which accounts for nearly 84% of the overall increase in demand between 2005 and 2030 (Khan et al., 2009). …"
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Estimating Economic and Environmental Benefits of Urban Trees in Desert Regions
منشور في 2020"…<p>Trees in urban areas have a significant impact on air quality and other environmental issues. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
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Revisiting the economic theory of crime A state-level analysis in India
منشور في 2023"…<p dir="ltr">The economic theory of crime tends to suggest that deterrence variables have a significant impact on crime rates in a society. …"
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Evaluating the economic impact of clinical pharmacist interventions in the women’s health setting in Qatar
منشور في 2025"…The sensitivity analysis confirmed that the outcomes are robust, demonstrating a 100% probability for positive economic benefits in all simulated cases.</p><h3>Conclusion</h3><p dir="ltr">Although there was an observed increase in resource utilization resulting from clinical pharmacists’ interventions, this study highlights their crucial role in mitigating the costs associated with preventable adverse drug events.…"
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Thermo-economic Optimization of Hybrid Combined Power Cycles Using Heliostat Field Collector
منشور في 2016احصل على النص الكامل
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
منشور في 2022"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
منشور في 2023"…<p>Most existing studies have focused on examining the impact of labor remittance outflows on economic growth in the receiving countries, with limited attention given to the sending countries. …"
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
منشور في 2023"…Most existing studies have focused on examining the impact of labor remittance outflows on economic growth in the receiving countries, with limited attention given to the sending countries. …"
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