A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"

Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis حسب Muhammad U. Sohail (9522515)

"…</p> <h2>Results</h2> <p>The data demonstrated a significant increase in microbiome diversity denoted by higher relative abundances of phylum Proteobacteria (p = 0.031), Fusobacteria (p = 0.044) and genus Streptococcus (p ≤ 0.001) in the infected group relative to the control. …"

Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes حسب Abu Saleh Md Moin (6189512)

"…PPBP and THBS1 tended to increase at hypoglycemia in both cohorts, though reached significance only in controls (p < 0.05), returning to BL levels post-hypoglycemia. …"

Effect of acute and chronic moderate alcohol consumption on fasted and postprandial lipemia in the rat حسب Daher, Costantine F.

"…Similar conditions also results in increased total phospholipid and cholesterol content of CM but not of VLDL, indicating an enhanced liver bile secretion into the gut; however, a significant increase in plasma VLDL concentration is observed. …"
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In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML) حسب Lteif, Anthony

"…WEHI-3 cells were treated with increasing concentrations of COE to determine the IC50 after 24, 48 and 72-hours post treatment. …"
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Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis حسب Abdullah Bin Kamran (22565237)

"…</p><h3>Conclusion</h3><p dir="ltr">Tirofiban as an adjunct to standard antiplatelet therapy in AIS patients significantly improves functional outcomes and reduces neurological impairment without increasing the risk of sICH.…"

Effect of Acute and Chronic Moderate Red or White Wine Consumption on Fasted and Postprandial Lipemia in the Rat حسب Daher, Costantine F.

"…Phospholipid and cholesterol contents of CM, but not very-low-density lipoprotein (VLDL), were increased, indicating enhanced liver bile secretion; however, a significant increase in plasma VLDL concentration was observed. …"
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Factors affecting job satisfaction among acute care nurses working in rural and urban settings حسب Yasin M. Yasin (14779381)

"…Participants (N=349) completed the Acute Care Nurses’ Job Satisfaction Scale and The Anticipated Turnover Scale. …"

Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…With respect to the proteins studied, treatment with Urtica dioica extract significantly increased the expression of the pro-apoptotic protein Bax with concomitant decrease in the anti-apoptotic protein Bcl-2 expression. …"
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Acute Myeloid Leukemia in Qatar (2010–2016): Clinical, Biological, and Prognostic Factors and Treatment Outcomes حسب Halima El Omri (14778790)

"…Prognostic factors including age, gender, white blood cell count, and risk stratification were not significantly associated with treatment outcomes, whereas response to treatment vs. failure was significantly associated with the outcome (<i>p</i> = 0.01). …"

Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model حسب Kobeissy, Firas

"…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway حسب Hodroj, Mohammad Hassan

"…The aim of this study is to investigate the possible synergism between TP and andrographolide in acute myeloid cells in vitro. Materials and methods U937 acute myeloid leukemic cells were cultured using Roswell Park Memorial Institute (RPMI) medium and then treated for 24 h with TP and andrographolide prepared through the dilution of dimethyl sulfoxide (DMSO) stocks with RPMI on the day of treatment. …"
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Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. حسب Daher, Costantine F.

"…All juices significantly increased VLDL apolipoprotein B [apoB] secretion,but plasma total apoB concentrations were highest in the grapefruit group and lowest in the orange andpineapple groups. …"
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Evaluation of the risk of acute kidney injury with the use of piperacillin/tazobactam among adult critically ill patients حسب Mohamed O. Saad (11659429)

"…<h3>Purpose</h3><p dir="ltr">Piperacillin/tazobactam (PT), when combined with vancomycin, is associated with an increased risk of acute kidney injury (AKI). It is not known whether PT alone is associated with a higher incidence of AKI compared to other β-lactams among critically ill patients. …"

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy حسب Fazle Rakib (5768069)

"…Furthermore, there is a decrease in the lipid order (disorder), which leads to an increase in acyl chain fluidity in injured rats. The results suggest acute TBI damages brain tissues mechanically rather than chemical alterations. …"

Metabolic and nutritional aspects of acute renal failure in critically Ill patients requiring continuous renal replacement therapy حسب Wooley, Jennifer A.

"…As such, concomitant clinical conditions significantly affect patient outcome. Poor nutritional status is a major factor in increasing patients' morbidity and mortality. …"
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Effect of acute and chronic grapefruit, orange and pineaple juice consumption upon blood lipoprotein synthesis and metabolism in the rat. (c2004) حسب Abou-Khalil, Jamil

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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002) حسب Berberi, Rania

"…In the acute alcohol study, the co-administration of a whisky dose with the fat load resulted in significant increases in plasma triacylglycerol (TAG) and cholesterol concentrations. …"
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