يعرض 1 - 20 نتائج من 117 نتيجة بحث عن '(( significant ((large decrease) OR (largest decrease)) ) OR ( significant alterations based ))', وقت الاستعلام: 0.11s تنقيح النتائج
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    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

    منشور في 2024
    "…</i>) where we quantify over 18,000 unique peptides from nearly 3000 proteins in more than 320 blood samples from a multi-ethnic cohort in a bottom-up, peptide-centric, mass spectrometry-based proteomics approach. We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…"
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …"
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    A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

    منشور في 2022
    "…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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    Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study حسب Jonas Ellegaard Nielsen (21633062)

    منشور في 2024
    "…Pathway analysis of significantly altered metabolites in the validation set revealed that they are involved in branched-chain amino acids (BCAAs) and energy metabolism (glycolysis and gluconeogenesis). …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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    A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

    منشور في 2021
    "…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …"
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    Application of surfactants in enhancing oil recovery from tight carbonates: Physicochemical properties and core flooding experiments حسب Osama Massarweh (17012217)

    منشور في 2023
    "…It was shown that the presence of the surfactants and the increase in salinity both caused a significant reduction in the oil-water IFT. Additionally, all surfactant formulations altered the wettability of carbonate rock from intermediate-to water-wet conditions. …"
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    The synergistic effects of cationic surfactant and smart seawater on the recovery of medium-viscosity crude oil from low-permeability carbonates حسب Osama Massarweh (17012217)

    منشور في 2023
    "…The use of smart SW and CTAB significantly altered the wettability of carbonate rock towards water-wet and reduced the interfacial tension (IFT) between crude oil and water, reaching levels below 0.087 mN/m. …"
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    COVID-19 biomarkers for severity mapped to polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

    منشور في 2020
    "…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …"
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    Kernel-Ridge-Regression-Based Randomized Network for Brain Age Classification and Estimation حسب Raveendra Pilli (21633287)

    منشور في 2024
    "…Moreover, the proposed algorithm demonstrated excellent prediction accuracy with a mean absolute error (MAE) of <b>3.89</b> years, <b>3.64 </b>years, and <b>4.49</b> years for GM, WM, and CSF regions, confirming that changes in WM volume are significantly associated with normal brain aging. Additionally, voxel-based morphometry (VBM) examines age-related anatomical alterations in different brain regions in GM, WM, and CSF tissue volumes.…"
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    Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends حسب Isra E. Gilani (17019066)

    منشور في 2024
    "…In addition, desalination plants consume significant amounts of energy, which contribute to carbon emissions and global warming. …"
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    A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus حسب Maria W. Smith (18807382)

    منشور في 2014
    "…Sequences of target oligonucleotides were altered to demonstrate that (i) any mutation of the restriction site reduced the signal to zero; (ii) double and triple point mutations of sequences flanking the restriction site reduced restriction to 50–80% of the positive control; and (iii) a minimum of a 16-bp target-probe dsDNA hybrid was required for significant cleavage. …"
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