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يعرض 1 - 20 نتائج من 119 نتيجة بحث عن '(( significant ((large decrease) OR (largest decrease)) ) OR ( significant alterations data ))', وقت الاستعلام: 0.12s تنقيح النتائج
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    Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling حسب Md Mizanur Rahman (14603354)

    منشور في 2018
    "…Our data collectively suggest that Nox2 is implicated in HFD-induced deleterious bone remodeling by enhancing bone marrow adipogenesis and osteoclastogenesis. …"
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    A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

    منشور في 2022
    "…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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    Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition حسب Ramesh Elango (7542068)

    منشور في 2021
    "…</p><h3>Conclusions</h3><p dir="ltr">Taken together, our data provides a comprehensive view of transcriptome alterations in the coding and noncoding transcriptome in TNBC in response to DNMT inhibition.…"
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    A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

    منشور في 2021
    "…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …"
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    Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

    منشور في 2020
    "…The observed impaired sorting was caused by reduced cholesterol levels and subsequent distortion of the lipid rafts. The data presented confirm perturbation of ER homeostasis in DSS-treated Caco-2 cells, accompanied by impairment of membrane and protein trafficking resulting in altered membrane integrity, cellular polarity, and hence disrupted barrier function.…"
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    Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation حسب Fawaz Kserawi (16904859)

    منشور في 2022
    "…Multiple approaches were proposed in the literature to preserve the privacy of consumers by altering the data via additive noise, masking, or other data obfuscation techniques. …"
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    Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function حسب Muge Sarper (3855454)

    منشور في 2017
    "…</p><h3>Conclusions</h3><p dir="ltr">These data indicate MMP-8 is a vital component of the myoepithelial tumour-suppressor function. …"
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    Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype حسب Duaa W. Al-Sadeq (10976754)

    منشور في 2022
    "…</li><li>Circular Dichroism experiments suggested that the p.R336C mutation does not significantly alter the secondary structure of the CBS protein.…"
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    Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket حسب Angelos Thanassoulas (2822861)

    منشور في 2023
    "…We then performed ITC experiments to investigate and compare the interactions of CaMWT and CaME105A mutant protein with two synthetic peptides that correspond to the two aforementioned human RyR2 regions, which we have proposed to contribute to the RyR2 CaM-binding pocket. Our data reveal that the E105A mutation has a significant negative effect on the interaction of CaM with both RyR2 regions in the presence and absence of Ca<sup>2+</sup>, highlighting the potential contribution of these two human RyR2 regions to an RyR2 CaM-binding pocket, which may be essential for physiological CaM/RyR2 association and thus channel regulation.…"
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    COVID-19 biomarkers for severity mapped to polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

    منشور في 2020
    "…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …"
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