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alterations data » alterations _ (توسيع البحث)
larger » large (توسيع البحث)
decrease » increase (توسيع البحث)
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Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
منشور في 2018"…Our data collectively suggest that Nox2 is implicated in HFD-induced deleterious bone remodeling by enhancing bone marrow adipogenesis and osteoclastogenesis. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Taken together, our data provides a comprehensive view of transcriptome alterations in the coding and noncoding transcriptome in TNBC in response to DNMT inhibition.…"
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Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line
منشور في 2020"…The observed impaired sorting was caused by reduced cholesterol levels and subsequent distortion of the lipid rafts. The data presented confirm perturbation of ER homeostasis in DSS-treated Caco-2 cells, accompanied by impairment of membrane and protein trafficking resulting in altered membrane integrity, cellular polarity, and hence disrupted barrier function.…"
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Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation
منشور في 2022"…Multiple approaches were proposed in the literature to preserve the privacy of consumers by altering the data via additive noise, masking, or other data obfuscation techniques. …"
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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
منشور في 2017"…</p><h3>Conclusions</h3><p dir="ltr">These data indicate MMP-8 is a vital component of the myoepithelial tumour-suppressor function. …"
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Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype
منشور في 2022"…</li><li>Circular Dichroism experiments suggested that the p.R336C mutation does not significantly alter the secondary structure of the CBS protein.…"
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Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
منشور في 2023"…We then performed ITC experiments to investigate and compare the interactions of CaMWT and CaME105A mutant protein with two synthetic peptides that correspond to the two aforementioned human RyR2 regions, which we have proposed to contribute to the RyR2 CaM-binding pocket. Our data reveal that the E105A mutation has a significant negative effect on the interaction of CaM with both RyR2 regions in the presence and absence of Ca<sup>2+</sup>, highlighting the potential contribution of these two human RyR2 regions to an RyR2 CaM-binding pocket, which may be essential for physiological CaM/RyR2 association and thus channel regulation.…"
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
منشور في 2018"…Solar energy has the largest untapped reserve in energy and is one of the fastest emerging energy markets. …"
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Effect of consanguinity on birth weight for gestational age in a developing country
منشور في 2007"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…Also, there was a significant decrease in p-Erk and p-Akt protein levels. …"
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. …"
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Genome-wide differential expression profiling of long non-coding RNAs (lncRNAs) in pancreatic cells derived from FOXA2-/- iPSCs
منشور في 2023"…</p> <p>Conclusion: Our results showed a strong correlation of lncRNAs to several key pancreatic genes and TFs during pancreatic differentiation. Furthermore, these data suggest that the FOXA2-related defective pancreatic islet development is associated with significant alterations in the expression profile of lncRNAs.…"
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Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
منشور في 2016"…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…When compared to control specimens, evaluation of epigenetic alterations in rat tumor cells in vivo showed significant dose-dependent decrease in lysine methylation status of H3K4m3 and H3K9m3 and dose-dependent increase in lysine acetylation in H4K16ac levels (H4K20m3 was not changed) in treated groups. …"
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Stemming cardiovascular diseases in Qatar
منشور في 2015"…“Both Qatari nationals and expatriates should adopt healthier lifestyles to reduce the prevalence of these risk factors,” says Christos. Diabetes was the largest preventable risk factor to decrease heart attacks and strokes.…"