بدائل البحث:
mutations based » simulation based (توسيع البحث)
larger » large (توسيع البحث)
decrease » increase (توسيع البحث)
mutations based » simulation based (توسيع البحث)
larger » large (توسيع البحث)
decrease » increase (توسيع البحث)
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"
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Mutational landscape of aggressive cutaneous squamous cell carcinoma
منشور في 2017"…Significantly mutated genes were identified with MutSig or complementary methods developed to specifically identify candidate tumor suppressors based upon their inactivating mutation bias. …"
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article -
4
A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus
منشور في 2014"…Sequences of target oligonucleotides were altered to demonstrate that (i) any mutation of the restriction site reduced the signal to zero; (ii) double and triple point mutations of sequences flanking the restriction site reduced restriction to 50–80% of the positive control; and (iii) a minimum of a 16-bp target-probe dsDNA hybrid was required for significant cleavage. …"
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A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">All affected individuals presented with a short stature without gross skeletal anomalies and significantly reduced serum GH levels. Genetic mapping revealed a homozygous nonsense mutation [NM_000823:c.G214T:p.…"
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Empirical Evaluation of Extended Finite State Machine Test Suites
منشور في 2022احصل على النص الكامل
doctoralThesis -
7
The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects
منشور في 2022"…We did not detect any homozygous FH or autosomal recessive mutations in our study cohort. This pioneering study provides a reliable estimate of FH prevalence in Qatar based on a significantly large population-based cohort, whilst uncovering the spectrum of genetic variants associated with FH.…"
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Integration of nonparametric fuzzy classification with an evolutionary-developmental framework to perform music sentiment-based analysis and composition
منشور في 2019"…However, few methods have targeted sentiment-based music composition: generating music that expresses human emotions. …"
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9
Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
منشور في 2018"…Solar energy has the largest untapped reserve in energy and is one of the fastest emerging energy markets. …"
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10
Effect of consanguinity on birth weight for gestational age in a developing country
منشور في 2007"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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11
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…Also, there was a significant decrease in p-Erk and p-Akt protein levels. …"
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12
Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. …"
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13
Can plasma vitamin C predict survival in stage IV colorectal cancer patients? Results of a prospective cohort study
منشور في 2023"…PFS did not differ based on vitamin C deficiency and patients with BRAF and KRAS mutations did not have significant differences in vitamin C levels. …"
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14
Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
منشور في 2016"…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …"
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15
Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes
منشور في 2024"…This approach involved screening a mutational landscape comprising 57 mutants to identify modifications that yield significant enhancements in binding efficacy and stability.…"
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Stemming cardiovascular diseases in Qatar
منشور في 2015"…“Both Qatari nationals and expatriates should adopt healthier lifestyles to reduce the prevalence of these risk factors,” says Christos. Diabetes was the largest preventable risk factor to decrease heart attacks and strokes.…"
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Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
منشور في 2023"…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …"
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18
Why do some countries produce more capital intensive output than others?
منشور في 2016"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
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article -
19
Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
منشور في 2023"…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …"
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20
Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers
منشور في 2023احصل على النص الكامل
doctoralThesis