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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
منشور في 2021"…On the demographic side, the massive external population migration that trickled towards the city resulted in a major defect in its demographic structure, which represented a decrease in the percentage of the citizen population to only about 10% of the non-citizen population. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Mobile Energy Storage Systems for Benefit Maximization in Resilient Smart Grids
منشور في 2025احصل على النص الكامل
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Scatter search for protein structure prediction. (c2008)
منشور في 2008احصل على النص الكامل
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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A new tabu search algorithm for the long-term hydro scheduling problem
منشور في 2002"…The proposed implementation contributes to the enhancement of speed and convergence of the original tabu search algorithm (TSA). A significant reduction in the objective function over previous classical optimization methods and a simulated annealing algorithm has been achieved. …"
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Performance and low power driven VLSI standard cell placement usingtabu search
منشور في 2002"…We engineer a well-known optimization technique namely tabu search (TS) (Sait and Youssef, 1999) for the performance and low power driven VLSI standard cell placement problem (Sait and Youssef, 1995; Minhas, 2001). …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Matheuristic Fixed Set Search Applied to the Two-Stage Capacitated Facility Location Problem
منشور في 2025"…<p dir="ltr">This paper addresses the Two-Stage Capacitated Facility Location Problem (TSCFLP), a challenging optimization problem with significant applications in supply chain network design. …"
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Fixed set search applied to the multi-objective minimum weighted vertex cover problem
منشور في 2022"…<p dir="ltr">The Fixed Set Search (FSS) is a novel metaheuristic that adds a learning mechanism to the Greedy Randomized Adaptive Search Procedure (GRASP). …"
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"A Tabu Search Approach for the Design of Variable Structure Load Frequency Controller Incorporating Model Nonlinearities"
منشور في 2007"…The proposed method formulates the design of VSC as an optimization problem and utilizes Tabu Search Algorithm (TS) to find the optimal settings of the controller. …"
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article