Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

A case of cat-scratch disease with unusual ophthalmic manifestations حسب Ghazi, Nicola G.

"…We report a case of cat-scratch disease with unusual posterior segment manifestations. …"
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The Use of the Gene Expression Omnibus (GEO) Database to Study Gene Expression and Methylation Patterns in Cases of Preterm Birth and Associated Diseases حسب Tala Abuarja (17075070)

"…</p> <h3>Conclusion</h3> <p>The utilization of GEO to analyse gene expression and methylation patterns in cases of PTB and associated diseases has linked various significant genes in potentially impacting such cases. …"

Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report حسب Mohammed Abdulgayoom (14777791)

"…<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. …"

Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

"…The ability to detect statistical relevant changes in the interaction patterns induced by the progression of the disease can lead to the discovery of novel relevant signatures. …"

Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

"…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…"

The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl حسب MOHAMED, SHAMSELDIN SAEED

"…On the other hand, the same study proved that the grid system and the villa model are the main reason behind the urban sprawl of the city. …"
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Refractory cold agglutinin disease successfully treated with daratumumab. A case report and review of literature حسب Abdelaziz Mohamed (14777668)

"…</p><h3>Conclusion</h3><p dir="ltr">Our case is the third reported case of refractory CAD successfully treated with daratumumab, which suggests that daratumumab might be a potential agent for the treatment and control of refractory Cold Agglutinin Disease.…"

Diagnostic Dilemma: Adult Onset Still’s Disease Mimicking Lymphoma—A Case Report and Literature Review حسب Mohannad N. AbuHaweeleh (22928704)

"…</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">AOSD presents a significant diagnostic challenge due to its rarity and symptom overlap with infections, malignancies, and autoimmune diseases. …"

Atypical IgG4‐related disease limited to the sino‐nasal cavity: A case report حسب Ahmed Shaikh (14777452)

"…<p></p><div> <p>Given the overlapping clinical features of sino-nasal immunoglobulin 4-related disease (IgG4-RD) to rhinitis or rhinosinusitis, this paper aims to delineate this rare, isolated manifestation significant to physicians for their daily practice and researchers contributing to this field.…"

Bilateral basal ganglia calcifications and Graves' disease in a young patient: A very rare association (case report) حسب Lina Okar (14777164)

"…Here, we report the first case that suggests a possible correlation between Graves' disease and basal ganglia calcifications.…"

Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review حسب Mousa Hussein (14137052)

"…Cryptococcus infection is an opportunistic fungal infection that can occur in patients receiving anti-TNF-α treatment. We report a rare case of isolated pulmonary cryptococcosis in a patient undergoing anti-TNF-α therapy for Crohn's disease. …"

Dilemma of Tocilizumab therapy for a patient with critical COVID‐19 disease and neutropenia: Case report and review of the literature حسب Ahmad Al Bishawi (14148810)

"…<p>Infection following SARS-Co V-2 leading to COVID-19 disease is associated with significant morbidity and mortality. …"

Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

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A young patient with Graves' disease presenting with a triad of heart failure, pancytopenia, and jaundice: A case report حسب Mohamed Kamal Sabra (17075230)

"…Delayed diagnosis and management of Graves' disease could lead to serious systemic sequelae. We describe a case of a young man who presented with progressive cough, increased abdominal girth and ankle swelling for a few months. …"

Clinical characteristics and outcomes of patients with TSH-secreting pituitary adenoma and Graves’ disease - a case report and systematic review حسب Adeel Ahmad Khan (14152953)

"…<h3>Background</h3><p dir="ltr">Coexistence of TSH-secreting pituitary adenoma (TSHoma) and Graves’ disease (GD) is rare and complicates the management decision.…"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"

Three cases of chronic photodermatitis successfully treated with upadacitinib حسب Hissa Al-Marri (22827287)

"…Here, we report three cases of chronic photodermatitis treated with upadacitinib, a selective Janus kinase 1 inhibitor, as monotherapy, which resulted in fast, significant and sustainable improvement of signs and symptoms, with a favourable safety and tolerability profile.…"

The Superiority of T2*MRI Over Serum Ferritin in the Evaluation of Secondary Iron Overload in a Chronic Kidney Disease Patient: A Case Report حسب Abdulrahman Al-Mashdali (16388474)

"…<p>Secondary iron overload is increasingly encountered in chronic kidney disease (CKD) patients because of the frequent use of parenteral iron products, especially in hemodialysis patients. …"

An unusual presentation of invasive aspergillosis with submandibular swelling in a 49‐year‐old man with end‐stage renal disease: A case report حسب Phool Iqbal (12217770)

"…Usually, the patient presents with fever and respiratory symptoms such as cough and haemoptysis. We present a case of IA in a 49-year-old man with end-stage renal disease who presented with fever and developed a submandibular swelling. …"