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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Effect of fasting on laryngopharyngeal reflux disease in male subjects
منشور في 2012"…To address the effect of fasting on laryngopharyngeal reflux disease (LPRD). …"
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COVID‐19 effect on patients with noncommunicable diseases: A narrative review
منشور في 2022"…This review aimed to assess the effect of COVID‐19 on different types of noncommunicable diseases and the severity it may cause to patients.…"
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Conclusions</h3><p dir="ltr">We show that our network differencing procedure can effectively and efficiently detect statistical significant network re-wirings in different conditions. …"
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
منشور في 2021"…On the other hand, the same study proved that the grid system and the villa model are the main reason behind the urban sprawl of the city. …"
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…We modeled HIV mortality using a Bayesian spatially explicit mixed-effects regression model that incorporates prior information on VR completeness. …"
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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
منشور في 2000"…The management of this disease is symptomatic, mainly based on the use of levodopa. …"
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masterThesis -
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Comparison of the Effects of 15 and 60 ,ug/kg Fentanyl Used for Induction of Anesthesia in Patients with Coronary Artery Disease
منشور في 1985"…We compared the effects of 15 and 60 [mu]g/kg fentanyl used for induction in 40 patients, 50-72 yr old, with coronary artery disease and mildly impaired ventricular contractility. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Mechanisms underlying the effects of caloric restriction on hypertension
منشور في 2022"…However, the mechanisms behind this effect are not yet fully understood, although an evolving view supports a significant impact of CR on vascular structure and function, specifically at the level of vascular endothelial cells, vascular smooth muscle cells along with their extracellular matrix (ECM). …"
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…Development of new, effective therapies for metastatic melanoma that target novel pathways associated with the genesis of metastatic disease is a major unmet clinical need. …"
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conferenceObject -
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Stemming cardiovascular diseases in Qatar
منشور في 2015"…The importance of diabetes as a risk factor, however, was found to be higher than other countries in the Gulf region and significantly higher than the US.</p><p>“Public health officials should design programmes to improve the prevention, diagnosis, and management of risk factors such as diabetes and hypertension,” says Christos, as well as work on effective awareness campaigns to create a culture of preventive health in Qatar.…"
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Antifungal activity of green synthesized selenium nanoparticles and their effect on physiological, biochemical, and antioxidant defense system of mango under mango malformation dis...
منشور في 2023"…The antioxidant defense system was also explored, and it was reported that green synthesized SeNPs significantly reduced the biotic stress by enhancing enzymatic and non-enzymatic activities. …"
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Coronary artery disease. (c2011)
منشور في 2011احصل على النص الكامل
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masterThesis -
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